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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]
| Target ID |
GM-SE0660
|
| Target Name |
AMH
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
268
|
| Gene ID |
101080263 (Felis catus), 102148318 (Equus caballus), 11705 (Mus musculus), 25378 (Rattus norvegicus) 268 (Homo sapiens), 280718 (Bos taurus), 485072 (Canis lupus familiaris), 717539 (Macaca mulatta)
|
| Target Alternative Names |
AMH,Amh,Anti-Muellerian hormone (AMH),MIF,MIS,Mis,Muellerian-inhibiting factor,Muellerian-inhibiting substance (MIS)
|
| Uniprot Accession |
P27106,P49000,P03971,P03972
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Diagnostics Biomarker
|
| Disease |
Hodgkin's lymphoma
|
| Disease from KEGG |
cAMP signaling pathway, Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway
|
| Gene Ensembl |
ENSECAG00000036148, ENSMUSG00000035262, ENSG00000104899, ENSBTAG00000025452, ENSCAFG00845012417, ENSMMUG00000058911
|
Pre-made viral vector of AMH cDNA Clones/ORF Plasmid
AMH siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo268 | Pre-made Human AMH/MIF/MIS siRNA oligo Duplex | 268 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25378 | Pre-made Rat Amh/MIS siRNA oligo Duplex | 25378 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11705 | Pre-made Mouse Amh/MIS siRNA oligo Duplex | 11705 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717539 | Pre-made Cynomolgus/Rhesus macaque AMH siRNA oligo Duplex | 717539 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080263 | Pre-made Cat/Feline AMH siRNA oligo Duplex | 101080263 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485072 | Pre-made Dog/Canine AMH/Mis siRNA oligo Duplex | 485072 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280718 | Pre-made Bovines/Cattle AMH siRNA oligo Duplex | 280718 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102148318 | Pre-made Equine/Horse AMH siRNA oligo Duplex | 102148318 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AMH antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0660-Ab | Human | Anti-Human AMH monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-SE0660-Ab | Rat | Anti-Rat AMH monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-SE0660-Ab | Mouse | Anti-Mouse AMH monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-SE0660-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AMH monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-SE0660-Ab | Cat/Feline | Anti-Cat/Feline AMH monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-SE0660-Ab | Dog/Canine | Anti-Dog/Canine AMH monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-SE0660-Ab | Bovines/Cattle | Anti-Bovines/Cattle AMH monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-SE0660-Ab | Equine/Horse | Anti-Equine/Horse AMH monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
AMH recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0660-Ag | Human | Human AMH recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0660-Ag | Rat | Rat AMH recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0660-Ag | Mouse | Mouse AMH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0660-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AMH recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0660-Ag | Cat/Feline | Cat/Feline AMH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0660-Ag | Dog/Canine | Dog/Canine AMH recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0660-Ag | Bovines/Cattle | Bovines/Cattle AMH recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0660-Ag | Equine/Horse | Equine/Horse AMH recombinant protein | Mammalian cell | Detail |