Recombinant multi-species IGLL1/CD179b protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGLL1/CD179b protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 14.1,AGM2,CD179 antigen-like family member B,CD179b,IGL1,IGL5,IGLJ14.1,IGLL,IGLL1,IGO,IGVPB,Ig lambda-5,Igl-5,Igll,Igll1,Immunoglobulin lambda-like polypeptide 1,Immunoglobulin omega polypeptide,Immunoglobulin-related protein 14.1,Lambda5,VPREB2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0620-Ag-1/ GM-Tg-hg-SE0620-Ag-2 | Human IGLL1/CD179b protein | Human |
| GM-Tg-rg-SE0620-Ag-1/ GM-Tg-rg-SE0620-Ag-2 | Rat IGLL1/CD179b protein | Rat |
| GM-Tg-mg-SE0620-Ag-1/ GM-Tg-mg-SE0620-Ag-2 | Mouse IGLL1/CD179b protein | Mouse |
| GM-Tg-cynog-SE0620-Ag-1/ GM-Tg-cynog-SE0620-Ag-2 | Cynomolgus/Rhesus macaque IGLL1/CD179b protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0620-Ag-1/ GM-Tg-felg-SE0620-Ag-2 | Feline IGLL1/CD179b protein | Feline |
| GM-Tg-cang-SE0620-Ag-1/ GM-Tg-cang-SE0620-Ag-2 | Canine IGLL1/CD179b protein | Canine |
| GM-Tg-bovg-SE0620-Ag-1/ GM-Tg-bovg-SE0620-Ag-2 | Bovine IGLL1/CD179b protein | Bovine |
| GM-Tg-equg-SE0620-Ag-1/ GM-Tg-equg-SE0620-Ag-2 | Equine IGLL1/CD179b protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0620-Ag-1/ GM-Tg-hg-SE0620-Ag-2;
GM-Tg-rg-SE0620-Ag-1/ GM-Tg-rg-SE0620-Ag-2;
GM-Tg-mg-SE0620-Ag-1/ GM-Tg-mg-SE0620-Ag-2; GM-Tg-cynog-SE0620-Ag-1/ GM-Tg-cynog-SE0620-Ag-2; GM-Tg-felg-SE0620-Ag-1/ GM-Tg-felg-SE0620-Ag-2; GM-Tg-cang-SE0620-Ag-1/ GM-Tg-cang-SE0620-Ag-2; GM-Tg-bovg-SE0620-Ag-1/ GM-Tg-bovg-SE0620-Ag-2; GM-Tg-equg-SE0620-Ag-1/ GM-Tg-equg-SE0620-Ag-2 |
| Products Name | IGLL1/CD179b protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | IGLL1/CD179b |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGLL1/CD179b protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.