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Target
sublocation: Secreted Protein/Potential Cytokines.
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0620
|
| Target Name |
IGLL1/CD179b
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3543
|
| Gene ID |
107000597 (Macaca mulatta), 16136 (Mus musculus), 3543 (Homo sapiens), 407114 (Bos taurus)
|
| Target Alternative Names |
14.1,AGM2,CD179 antigen-like family member B,CD179b,IGL1,IGL5,IGLJ14.1,IGLL,IGLL1,IGO,IGVPB,Ig lambda-5,Igl-5,Igll,Igll1,Immunoglobulin lambda-like polypeptide 1,Immunoglobulin omega polypeptide,Immunoglobulin-related protein 14.1,Lambda5,VPREB2
|
| Uniprot Accession |
P20764,P15814
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Gene Ensembl |
ENSMMUG00000007341, ENSMUSG00000075370, ENSG00000128322
|
IGLL1/CD179b siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3543 | Pre-made Human IGLL1/IGO/14.1 siRNA oligo Duplex | 3543 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16136 | Pre-made Mouse Igll1/Igll/Igl-5 siRNA oligo Duplex | 16136 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107000597 | Pre-made Cynomolgus/Rhesus macaque IGLL1 siRNA oligo Duplex | 107000597 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407114 | Pre-made Bovines/Cattle IGLL1 siRNA oligo Duplex | 407114 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
IGLL1/CD179b antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0620-Ab | Human | Anti-Human IGLL1/CD179b monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0620-Ab | Mouse | Anti-Mouse IGLL1/CD179b monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0620-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGLL1/CD179b monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0620-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGLL1/CD179b monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
IGLL1/CD179b recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0620-Ag | Human | Human IGLL1/CD179b recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0620-Ag | Mouse | Mouse IGLL1/CD179b recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0620-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGLL1/CD179b recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0620-Ag | Bovines/Cattle | Bovines/Cattle IGLL1/CD179b recombinant protein | Mammalian cell | Detail |
