Recombinant multi-species KU70/XRCC6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KU70/XRCC6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5'-deoxyribose-5-phosphate lyase Ku70 (5'-dRP lyase Ku70),70 kDa subunit of Ku antigen,70kDa,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit (CTC75,CTC75,CTCBF,CTCBF),DNA repair protein XRCC6,G22P1,G22p1,KU70,Ku70,Kup70,Lupus Ku autoantigen protein p70 (Ku70),ML8,TLAA,Thyroid-lupus autoantigen (TLAA),X-ray repair complementing defective repair in Chinese hamster cells 6,X-ray repair cross-complementing protein 6,XRCC6,Xrcc6

Target products collectionGo to KU70/XRCC6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0563-Ag-1/ GM-Tg-hg-SE0563-Ag-2 Human KU70/XRCC6 protein Human
GM-Tg-rg-SE0563-Ag-1/ GM-Tg-rg-SE0563-Ag-2 Rat KU70/XRCC6 protein Rat
GM-Tg-mg-SE0563-Ag-1/ GM-Tg-mg-SE0563-Ag-2 Mouse KU70/XRCC6 protein Mouse
GM-Tg-cynog-SE0563-Ag-1/ GM-Tg-cynog-SE0563-Ag-2 Cynomolgus/Rhesus macaque KU70/XRCC6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0563-Ag-1/ GM-Tg-felg-SE0563-Ag-2 Feline KU70/XRCC6 protein Feline
GM-Tg-cang-SE0563-Ag-1/ GM-Tg-cang-SE0563-Ag-2 Canine KU70/XRCC6 protein Canine
GM-Tg-bovg-SE0563-Ag-1/ GM-Tg-bovg-SE0563-Ag-2 Bovine KU70/XRCC6 protein Bovine
GM-Tg-equg-SE0563-Ag-1/ GM-Tg-equg-SE0563-Ag-2 Equine KU70/XRCC6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0563-Ag-1/ GM-Tg-hg-SE0563-Ag-2; GM-Tg-rg-SE0563-Ag-1/ GM-Tg-rg-SE0563-Ag-2;
GM-Tg-mg-SE0563-Ag-1/ GM-Tg-mg-SE0563-Ag-2; GM-Tg-cynog-SE0563-Ag-1/ GM-Tg-cynog-SE0563-Ag-2;
GM-Tg-felg-SE0563-Ag-1/ GM-Tg-felg-SE0563-Ag-2; GM-Tg-cang-SE0563-Ag-1/ GM-Tg-cang-SE0563-Ag-2;
GM-Tg-bovg-SE0563-Ag-1/ GM-Tg-bovg-SE0563-Ag-2; GM-Tg-equg-SE0563-Ag-1/ GM-Tg-equg-SE0563-Ag-2
Products Name KU70/XRCC6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KU70/XRCC6
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KU70/XRCC6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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