Recombinant multi-species TGFBR3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TGFBR3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
The Alternative Names of target: 1110036H20Rik,BGCAN,Betaglycan,TBRIII,TGF-beta receptor type 3,TGFBR3,TGFR-3,Tgfbr3,Transforming growth factor beta receptor III (TGF-beta receptor type III),Transforming growth factor beta receptor type 3,betaglycan

Target products collectionGo to TGFBR3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0500-Ag-1/ GM-Tg-hg-SE0500-Ag-2 Human TGFBR3 protein Human
GM-Tg-rg-SE0500-Ag-1/ GM-Tg-rg-SE0500-Ag-2 Rat TGFBR3 protein Rat
GM-Tg-mg-SE0500-Ag-1/ GM-Tg-mg-SE0500-Ag-2 Mouse TGFBR3 protein Mouse
GM-Tg-cynog-SE0500-Ag-1/ GM-Tg-cynog-SE0500-Ag-2 Cynomolgus/Rhesus macaque TGFBR3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0500-Ag-1/ GM-Tg-felg-SE0500-Ag-2 Feline TGFBR3 protein Feline
GM-Tg-cang-SE0500-Ag-1/ GM-Tg-cang-SE0500-Ag-2 Canine TGFBR3 protein Canine
GM-Tg-bovg-SE0500-Ag-1/ GM-Tg-bovg-SE0500-Ag-2 Bovine TGFBR3 protein Bovine
GM-Tg-equg-SE0500-Ag-1/ GM-Tg-equg-SE0500-Ag-2 Equine TGFBR3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0500-Ag-1/ GM-Tg-hg-SE0500-Ag-2; GM-Tg-rg-SE0500-Ag-1/ GM-Tg-rg-SE0500-Ag-2;
GM-Tg-mg-SE0500-Ag-1/ GM-Tg-mg-SE0500-Ag-2; GM-Tg-cynog-SE0500-Ag-1/ GM-Tg-cynog-SE0500-Ag-2;
GM-Tg-felg-SE0500-Ag-1/ GM-Tg-felg-SE0500-Ag-2; GM-Tg-cang-SE0500-Ag-1/ GM-Tg-cang-SE0500-Ag-2;
GM-Tg-bovg-SE0500-Ag-1/ GM-Tg-bovg-SE0500-Ag-2; GM-Tg-equg-SE0500-Ag-1/ GM-Tg-equg-SE0500-Ag-2
Products Name TGFBR3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TGFBR3
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TGFBR3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.