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Target
sublocation: Secreted Protein/Potential Cytokines.
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
| Target ID |
GM-SE0500
|
| Target Name |
TGFBR3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7049
|
| Gene ID |
100060435 (Equus caballus), 101096404 (Felis catus), 21814 (Mus musculus), 29610 (Rattus norvegicus)
490163 (Canis lupus familiaris), 7049 (Homo sapiens), 705053 (Macaca mulatta), 784894 (Bos taurus)
|
| Target Alternative Names |
1110036H20Rik,BGCAN,Betaglycan,TBRIII,TGF-beta receptor type 3,TGFBR3,TGFR-3,Tgfbr3,Transforming growth factor beta receptor III (TGF-beta receptor type III),Transforming growth factor beta receptor type 3,betaglycan
|
| Uniprot Accession |
O88393,P26342,Q03167
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000019700, ENSMUSG00000029287, ENSCAFG00845016141, ENSG00000069702, ENSMMUG00000001742, ENSBTAG00000024269
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of TGFBR3 cDNA Clones/ORF Plasmid
TGFBR3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7049 | Pre-made Human TGFBR3/BGCAN/betaglycan siRNA oligo Duplex | 7049 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29610 | Pre-made Rat Tgfbr3/betaglycan siRNA oligo Duplex | 29610 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21814 | Pre-made Mouse Tgfbr3/TBRIII/1110036H20Rik siRNA oligo Duplex | 21814 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705053 | Pre-made Cynomolgus/Rhesus macaque TGFBR3 siRNA oligo Duplex | 705053 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096404 | Pre-made Cat/Feline TGFBR3 siRNA oligo Duplex | 101096404 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490163 | Pre-made Dog/Canine TGFBR3 siRNA oligo Duplex | 490163 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo784894 | Pre-made Bovines/Cattle TGFBR3 siRNA oligo Duplex | 784894 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060435 | Pre-made Equine/Horse TGFBR3 siRNA oligo Duplex | 100060435 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TGFBR3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0500-Ab | Human | Anti-Human TGFBR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0500-Ab | Rat | Anti-Rat TGFBR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0500-Ab | Mouse | Anti-Mouse TGFBR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0500-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TGFBR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0500-Ab | Cat/Feline | Anti-Cat/Feline TGFBR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0500-Ab | Dog/Canine | Anti-Dog/Canine TGFBR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0500-Ab | Bovines/Cattle | Anti-Bovines/Cattle TGFBR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0500-Ab | Equine/Horse | Anti-Equine/Horse TGFBR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
TGFBR3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0500-Ag | Human | Human TGFBR3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0500-Ag | Rat | Rat TGFBR3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0500-Ag | Mouse | Mouse TGFBR3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0500-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TGFBR3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0500-Ag | Cat/Feline | Cat/Feline TGFBR3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0500-Ag | Dog/Canine | Dog/Canine TGFBR3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0500-Ag | Bovines/Cattle | Bovines/Cattle TGFBR3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0500-Ag | Equine/Horse | Equine/Horse TGFBR3 recombinant protein | Mammalian cell | Detail |
