Recombinant multi-species SLIT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SLIT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
The Alternative Names of target: Drad-1,E030015M03Rik,E130320P19Rik,SLIL3,SLIT2,Slil3,Slit homolog 2 protein,Slit-2,Slit2,b2b1200.1Clo,mKIAA4141,slit-2

Target products collectionGo to SLIT2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0474-Ag-1/ GM-Tg-hg-SE0474-Ag-2 Human SLIT2 protein Human
GM-Tg-rg-SE0474-Ag-1/ GM-Tg-rg-SE0474-Ag-2 Rat SLIT2 protein Rat
GM-Tg-mg-SE0474-Ag-1/ GM-Tg-mg-SE0474-Ag-2 Mouse SLIT2 protein Mouse
GM-Tg-cynog-SE0474-Ag-1/ GM-Tg-cynog-SE0474-Ag-2 Cynomolgus/Rhesus macaque SLIT2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0474-Ag-1/ GM-Tg-felg-SE0474-Ag-2 Feline SLIT2 protein Feline
GM-Tg-cang-SE0474-Ag-1/ GM-Tg-cang-SE0474-Ag-2 Canine SLIT2 protein Canine
GM-Tg-bovg-SE0474-Ag-1/ GM-Tg-bovg-SE0474-Ag-2 Bovine SLIT2 protein Bovine
GM-Tg-equg-SE0474-Ag-1/ GM-Tg-equg-SE0474-Ag-2 Equine SLIT2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0474-Ag-1/ GM-Tg-hg-SE0474-Ag-2; GM-Tg-rg-SE0474-Ag-1/ GM-Tg-rg-SE0474-Ag-2;
GM-Tg-mg-SE0474-Ag-1/ GM-Tg-mg-SE0474-Ag-2; GM-Tg-cynog-SE0474-Ag-1/ GM-Tg-cynog-SE0474-Ag-2;
GM-Tg-felg-SE0474-Ag-1/ GM-Tg-felg-SE0474-Ag-2; GM-Tg-cang-SE0474-Ag-1/ GM-Tg-cang-SE0474-Ag-2;
GM-Tg-bovg-SE0474-Ag-1/ GM-Tg-bovg-SE0474-Ag-2; GM-Tg-equg-SE0474-Ag-1/ GM-Tg-equg-SE0474-Ag-2
Products Name SLIT2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SLIT2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SLIT2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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