Recombinant multi-species Alpha Antichymotrypsin/SERPINA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Alpha Antichymotrypsin/SERPINA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jun 2020]
The Alternative Names of target: AACT,ACT,Alpha Antichymotrypsin,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,GIG24,GIG25,SERPINA3,Serpin A3

Target products collectionGo to Alpha Antichymotrypsin/SERPINA3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0467-Ag-1/ GM-Tg-hg-SE0467-Ag-2 Human Alpha Antichymotrypsin/SERPINA3 protein Human
GM-Tg-rg-SE0467-Ag-1/ GM-Tg-rg-SE0467-Ag-2 Rat Alpha Antichymotrypsin/SERPINA3 protein Rat
GM-Tg-mg-SE0467-Ag-1/ GM-Tg-mg-SE0467-Ag-2 Mouse Alpha Antichymotrypsin/SERPINA3 protein Mouse
GM-Tg-cynog-SE0467-Ag-1/ GM-Tg-cynog-SE0467-Ag-2 Cynomolgus/Rhesus macaque Alpha Antichymotrypsin/SERPINA3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0467-Ag-1/ GM-Tg-felg-SE0467-Ag-2 Feline Alpha Antichymotrypsin/SERPINA3 protein Feline
GM-Tg-cang-SE0467-Ag-1/ GM-Tg-cang-SE0467-Ag-2 Canine Alpha Antichymotrypsin/SERPINA3 protein Canine
GM-Tg-bovg-SE0467-Ag-1/ GM-Tg-bovg-SE0467-Ag-2 Bovine Alpha Antichymotrypsin/SERPINA3 protein Bovine
GM-Tg-equg-SE0467-Ag-1/ GM-Tg-equg-SE0467-Ag-2 Equine Alpha Antichymotrypsin/SERPINA3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0467-Ag-1/ GM-Tg-hg-SE0467-Ag-2; GM-Tg-rg-SE0467-Ag-1/ GM-Tg-rg-SE0467-Ag-2;
GM-Tg-mg-SE0467-Ag-1/ GM-Tg-mg-SE0467-Ag-2; GM-Tg-cynog-SE0467-Ag-1/ GM-Tg-cynog-SE0467-Ag-2;
GM-Tg-felg-SE0467-Ag-1/ GM-Tg-felg-SE0467-Ag-2; GM-Tg-cang-SE0467-Ag-1/ GM-Tg-cang-SE0467-Ag-2;
GM-Tg-bovg-SE0467-Ag-1/ GM-Tg-bovg-SE0467-Ag-2; GM-Tg-equg-SE0467-Ag-1/ GM-Tg-equg-SE0467-Ag-2
Products Name Alpha Antichymotrypsin/SERPINA3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Alpha Antichymotrypsin/SERPINA3
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Alpha Antichymotrypsin/SERPINA3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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