Explore Alpha Antichymotrypsin/SERPINA3 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jun 2020]
| Target ID |
GM-SE0467
|
| Target Name |
Alpha Antichymotrypsin/SERPINA3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
12
|
| Gene ID |
101089197 (Felis catus), 12 (Homo sapiens), 480425 (Canis lupus familiaris), 574106 (Macaca mulatta)
|
| Target Alternative Names |
AACT,ACT,Alpha Antichymotrypsin,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,GIG24,GIG25,SERPINA3,Serpin A3
|
| Uniprot Accession |
P01011
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Diabetes type-2, Diabetic Nephropathy, Kidney transplant rejection, Non-small cell lung carcinoma, Acute appendicitis
|
| Gene Ensembl |
ENSG00000196136, ENSCAFG00845003163, ENSMMUG00000011218
|
Pre-made viral vector of Alpha Antichymotrypsin/SERPINA3 cDNA Clones/ORF Plasmid
Alpha Antichymotrypsin/SERPINA3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo12 | Pre-made Human SERPINA3/ACT/AACT siRNA oligo Duplex | 12 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574106 | Pre-made Cynomolgus/Rhesus macaque SERPINA3 siRNA oligo Duplex | 574106 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089197 | Pre-made Cat/Feline SERPINA3 siRNA oligo Duplex | 101089197 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480425 | Pre-made Dog/Canine SERPINA3 siRNA oligo Duplex | 480425 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
Alpha Antichymotrypsin/SERPINA3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0467-Ab | Human | Anti-Human Alpha Antichymotrypsin/SERPINA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0467-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Alpha Antichymotrypsin/SERPINA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0467-Ab | Cat/Feline | Anti-Cat/Feline Alpha Antichymotrypsin/SERPINA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0467-Ab | Dog/Canine | Anti-Dog/Canine Alpha Antichymotrypsin/SERPINA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Alpha Antichymotrypsin/SERPINA3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0467-Ag | Human | Human Alpha Antichymotrypsin/SERPINA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0467-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Alpha Antichymotrypsin/SERPINA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0467-Ag | Cat/Feline | Cat/Feline Alpha Antichymotrypsin/SERPINA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0467-Ag | Dog/Canine | Dog/Canine Alpha Antichymotrypsin/SERPINA3 recombinant protein | Mammalian cell | Detail |
