Recombinant multi-species ASC/TMS1/PYCARD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASC/TMS1/PYCARD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ASC,Apoptosis-associated speck-like protein containing a CARD,Asc,CARD5,Caspase recruitment domain-containing protein 5,PYCARD,PYD and CARD domain-containing protein,Pycard,TMS,TMS-1,TMS1,Target of methylation-induced silencing 1,hASC

Target products collectionGo to ASC/TMS1/PYCARD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0440-Ag-1/ GM-Tg-hg-SE0440-Ag-2 Human ASC/TMS1/PYCARD protein Human
GM-Tg-rg-SE0440-Ag-1/ GM-Tg-rg-SE0440-Ag-2 Rat ASC/TMS1/PYCARD protein Rat
GM-Tg-mg-SE0440-Ag-1/ GM-Tg-mg-SE0440-Ag-2 Mouse ASC/TMS1/PYCARD protein Mouse
GM-Tg-cynog-SE0440-Ag-1/ GM-Tg-cynog-SE0440-Ag-2 Cynomolgus/Rhesus macaque ASC/TMS1/PYCARD protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0440-Ag-1/ GM-Tg-felg-SE0440-Ag-2 Feline ASC/TMS1/PYCARD protein Feline
GM-Tg-cang-SE0440-Ag-1/ GM-Tg-cang-SE0440-Ag-2 Canine ASC/TMS1/PYCARD protein Canine
GM-Tg-bovg-SE0440-Ag-1/ GM-Tg-bovg-SE0440-Ag-2 Bovine ASC/TMS1/PYCARD protein Bovine
GM-Tg-equg-SE0440-Ag-1/ GM-Tg-equg-SE0440-Ag-2 Equine ASC/TMS1/PYCARD protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0440-Ag-1/ GM-Tg-hg-SE0440-Ag-2; GM-Tg-rg-SE0440-Ag-1/ GM-Tg-rg-SE0440-Ag-2;
GM-Tg-mg-SE0440-Ag-1/ GM-Tg-mg-SE0440-Ag-2; GM-Tg-cynog-SE0440-Ag-1/ GM-Tg-cynog-SE0440-Ag-2;
GM-Tg-felg-SE0440-Ag-1/ GM-Tg-felg-SE0440-Ag-2; GM-Tg-cang-SE0440-Ag-1/ GM-Tg-cang-SE0440-Ag-2;
GM-Tg-bovg-SE0440-Ag-1/ GM-Tg-bovg-SE0440-Ag-2; GM-Tg-equg-SE0440-Ag-1/ GM-Tg-equg-SE0440-Ag-2
Products Name ASC/TMS1/PYCARD protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ASC/TMS1/PYCARD
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASC/TMS1/PYCARD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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