Recombinant multi-species PSMD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PSMD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. There is evidence that this proteasome and its subunits interact with viral proteins, including those of coronaviruses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2020]
The Alternative Names of target: 2410026J11Rik,26S proteasome non-ATPase regulatory subunit 1,26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112,P112,PSMD1,Psmd1,Rpn2,S1

Target products collectionGo to PSMD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0436-Ag-1/ GM-Tg-hg-SE0436-Ag-2 Human PSMD1 protein Human
GM-Tg-rg-SE0436-Ag-1/ GM-Tg-rg-SE0436-Ag-2 Rat PSMD1 protein Rat
GM-Tg-mg-SE0436-Ag-1/ GM-Tg-mg-SE0436-Ag-2 Mouse PSMD1 protein Mouse
GM-Tg-cynog-SE0436-Ag-1/ GM-Tg-cynog-SE0436-Ag-2 Cynomolgus/Rhesus macaque PSMD1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0436-Ag-1/ GM-Tg-felg-SE0436-Ag-2 Feline PSMD1 protein Feline
GM-Tg-cang-SE0436-Ag-1/ GM-Tg-cang-SE0436-Ag-2 Canine PSMD1 protein Canine
GM-Tg-bovg-SE0436-Ag-1/ GM-Tg-bovg-SE0436-Ag-2 Bovine PSMD1 protein Bovine
GM-Tg-equg-SE0436-Ag-1/ GM-Tg-equg-SE0436-Ag-2 Equine PSMD1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0436-Ag-1/ GM-Tg-hg-SE0436-Ag-2; GM-Tg-rg-SE0436-Ag-1/ GM-Tg-rg-SE0436-Ag-2;
GM-Tg-mg-SE0436-Ag-1/ GM-Tg-mg-SE0436-Ag-2; GM-Tg-cynog-SE0436-Ag-1/ GM-Tg-cynog-SE0436-Ag-2;
GM-Tg-felg-SE0436-Ag-1/ GM-Tg-felg-SE0436-Ag-2; GM-Tg-cang-SE0436-Ag-1/ GM-Tg-cang-SE0436-Ag-2;
GM-Tg-bovg-SE0436-Ag-1/ GM-Tg-bovg-SE0436-Ag-2; GM-Tg-equg-SE0436-Ag-1/ GM-Tg-equg-SE0436-Ag-2
Products Name PSMD1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PSMD1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PSMD1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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