Explore PSMD1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. There is evidence that this proteasome and its subunits interact with viral proteins, including those of coronaviruses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2020]
| Target ID |
GM-SE0436
|
| Target Name |
PSMD1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5707
|
| Gene ID |
100057015 (Equus caballus), 100683530 (Canis lupus familiaris), 101082082 (Felis catus), 511803 (Bos taurus) 5707 (Homo sapiens), 70247 (Mus musculus), 711724 (Macaca mulatta), 83806 (Rattus norvegicus)
|
| Target Alternative Names |
2410026J11Rik,26S proteasome non-ATPase regulatory subunit 1,26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112,P112,PSMD1,Psmd1,Rpn2,S1
|
| Uniprot Accession |
Q99460,Q3TXS7,O88761
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Alzheimer disease, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSECAG00000007845, ENSCAFG00845022206, ENSBTAG00000005119, ENSG00000173692, ENSMUSG00000026229, ENSMMUG00000011769
|
Pre-made viral vector of PSMD1 cDNA Clones/ORF Plasmid
PSMD1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5707 | Pre-made Human PSMD1/S1/P112 siRNA oligo Duplex | 5707 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83806 | Pre-made Rat Psmd1 siRNA oligo Duplex | 83806 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo70247 | Pre-made Mouse Psmd1/S1/P112 siRNA oligo Duplex | 70247 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711724 | Pre-made Cynomolgus/Rhesus macaque PSMD1 siRNA oligo Duplex | 711724 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082082 | Pre-made Cat/Feline PSMD1 siRNA oligo Duplex | 101082082 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100683530 | Pre-made Dog/Canine PSMD1 siRNA oligo Duplex | 100683530 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511803 | Pre-made Bovines/Cattle PSMD1 siRNA oligo Duplex | 511803 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057015 | Pre-made Equine/Horse PSMD1 siRNA oligo Duplex | 100057015 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PSMD1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0436-Ab | Human | Anti-Human PSMD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0436-Ab | Rat | Anti-Rat PSMD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0436-Ab | Mouse | Anti-Mouse PSMD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0436-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PSMD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0436-Ab | Cat/Feline | Anti-Cat/Feline PSMD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0436-Ab | Dog/Canine | Anti-Dog/Canine PSMD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0436-Ab | Bovines/Cattle | Anti-Bovines/Cattle PSMD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0436-Ab | Equine/Horse | Anti-Equine/Horse PSMD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PSMD1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0436-Ag | Human | Human PSMD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0436-Ag | Rat | Rat PSMD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0436-Ag | Mouse | Mouse PSMD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0436-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PSMD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0436-Ag | Cat/Feline | Cat/Feline PSMD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0436-Ag | Dog/Canine | Dog/Canine PSMD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0436-Ag | Bovines/Cattle | Bovines/Cattle PSMD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0436-Ag | Equine/Horse | Equine/Horse PSMD1 recombinant protein | Mammalian cell | Detail |