Recombinant multi-species LTBP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LTBP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 9430031G15Rik,9830146M04,ARCL2E,LTBP-1,LTBP1,Latent-transforming growth factor beta-binding protein 1,Ltbp-1,Ltbp1,Ltbp1L,TGF-beta1-BP-1,Tgfb,Transforming growth factor beta-1-binding protein 1 (TGF-beta1-BP-1),b2b1000Clo

Target products collectionGo to LTBP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0327-Ag-1/ GM-Tg-hg-SE0327-Ag-2 Human LTBP1 protein Human
GM-Tg-rg-SE0327-Ag-1/ GM-Tg-rg-SE0327-Ag-2 Rat LTBP1 protein Rat
GM-Tg-mg-SE0327-Ag-1/ GM-Tg-mg-SE0327-Ag-2 Mouse LTBP1 protein Mouse
GM-Tg-cynog-SE0327-Ag-1/ GM-Tg-cynog-SE0327-Ag-2 Cynomolgus/Rhesus macaque LTBP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0327-Ag-1/ GM-Tg-felg-SE0327-Ag-2 Feline LTBP1 protein Feline
GM-Tg-cang-SE0327-Ag-1/ GM-Tg-cang-SE0327-Ag-2 Canine LTBP1 protein Canine
GM-Tg-bovg-SE0327-Ag-1/ GM-Tg-bovg-SE0327-Ag-2 Bovine LTBP1 protein Bovine
GM-Tg-equg-SE0327-Ag-1/ GM-Tg-equg-SE0327-Ag-2 Equine LTBP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0327-Ag-1/ GM-Tg-hg-SE0327-Ag-2; GM-Tg-rg-SE0327-Ag-1/ GM-Tg-rg-SE0327-Ag-2;
GM-Tg-mg-SE0327-Ag-1/ GM-Tg-mg-SE0327-Ag-2; GM-Tg-cynog-SE0327-Ag-1/ GM-Tg-cynog-SE0327-Ag-2;
GM-Tg-felg-SE0327-Ag-1/ GM-Tg-felg-SE0327-Ag-2; GM-Tg-cang-SE0327-Ag-1/ GM-Tg-cang-SE0327-Ag-2;
GM-Tg-bovg-SE0327-Ag-1/ GM-Tg-bovg-SE0327-Ag-2; GM-Tg-equg-SE0327-Ag-1/ GM-Tg-equg-SE0327-Ag-2
Products Name LTBP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LTBP1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LTBP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.