Explore LTBP1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0327
|
| Target Name |
LTBP1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4052
|
| Gene ID |
100070522 (Equus caballus), 101084534 (Felis catus), 268977 (Mus musculus), 4052 (Homo sapiens)
475720 (Canis lupus familiaris), 510559 (Bos taurus), 59107 (Rattus norvegicus), 709607 (Macaca mulatta)
|
| Target Alternative Names |
9430031G15Rik,9830146M04,ARCL2E,LTBP-1,LTBP1,Latent-transforming growth factor beta-binding protein 1,Ltbp-1,Ltbp1,Ltbp1L,TGF-beta1-BP-1,Tgfb,Transforming growth factor beta-1-binding protein 1 (TGF-beta1-BP-1),b2b1000Clo
|
| Uniprot Accession |
Q8CG19,Q14766,Q00918
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Ovary Cancer, Dent disease, Pregnant state
|
| Disease from KEGG |
TGF-beta signaling pathway
|
| Gene Ensembl |
ENSECAG00000019691, ENSMUSG00000001870, ENSG00000049323, ENSCAFG00845013785, ENSBTAG00000019839, ENSMMUG00000021436
|
LTBP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4052 | Pre-made Human LTBP1/ARCL2E siRNA oligo Duplex | 4052 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo59107 | Pre-made Rat Ltbp1 siRNA oligo Duplex | 59107 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo268977 | Pre-made Mouse Ltbp1/Tgfb/Ltbp-1 siRNA oligo Duplex | 268977 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709607 | Pre-made Cynomolgus/Rhesus macaque LTBP1 siRNA oligo Duplex | 709607 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084534 | Pre-made Cat/Feline LTBP1 siRNA oligo Duplex | 101084534 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475720 | Pre-made Dog/Canine LTBP1 siRNA oligo Duplex | 475720 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510559 | Pre-made Bovines/Cattle LTBP1 siRNA oligo Duplex | 510559 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070522 | Pre-made Equine/Horse LTBP1 siRNA oligo Duplex | 100070522 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LTBP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0327-Ab | Human | Anti-Human LTBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0327-Ab | Rat | Anti-Rat LTBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0327-Ab | Mouse | Anti-Mouse LTBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0327-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LTBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0327-Ab | Cat/Feline | Anti-Cat/Feline LTBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0327-Ab | Dog/Canine | Anti-Dog/Canine LTBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0327-Ab | Bovines/Cattle | Anti-Bovines/Cattle LTBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0327-Ab | Equine/Horse | Anti-Equine/Horse LTBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
LTBP1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0327-Ag | Human | Human LTBP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0327-Ag | Rat | Rat LTBP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0327-Ag | Mouse | Mouse LTBP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0327-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LTBP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0327-Ag | Cat/Feline | Cat/Feline LTBP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0327-Ag | Dog/Canine | Dog/Canine LTBP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0327-Ag | Bovines/Cattle | Bovines/Cattle LTBP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0327-Ag | Equine/Horse | Equine/Horse LTBP1 recombinant protein | Mammalian cell | Detail |
