Recombinant multi-species LAMA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LAMA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]
The Alternative Names of target: BM600,E170,Epiligrin 170 kDa subunit (E170),Epiligrin subunit alpha,JEB2A,JEB2B,JEB2C,Kalinin subunit alpha,LAMA3,LAMNA,LOCS,Lama3,Lama3B,Laminin subunit alpha-3,Laminin-5 subunit alpha,Laminin-6 subunit alpha,Laminin-7 subunit alpha,Nicein subunit alpha,[a]3B
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0297-Ag-1/ GM-Tg-hg-SE0297-Ag-2 | Human LAMA3 protein | Human |
| GM-Tg-rg-SE0297-Ag-1/ GM-Tg-rg-SE0297-Ag-2 | Rat LAMA3 protein | Rat |
| GM-Tg-mg-SE0297-Ag-1/ GM-Tg-mg-SE0297-Ag-2 | Mouse LAMA3 protein | Mouse |
| GM-Tg-cynog-SE0297-Ag-1/ GM-Tg-cynog-SE0297-Ag-2 | Cynomolgus/Rhesus macaque LAMA3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0297-Ag-1/ GM-Tg-felg-SE0297-Ag-2 | Feline LAMA3 protein | Feline |
| GM-Tg-cang-SE0297-Ag-1/ GM-Tg-cang-SE0297-Ag-2 | Canine LAMA3 protein | Canine |
| GM-Tg-bovg-SE0297-Ag-1/ GM-Tg-bovg-SE0297-Ag-2 | Bovine LAMA3 protein | Bovine |
| GM-Tg-equg-SE0297-Ag-1/ GM-Tg-equg-SE0297-Ag-2 | Equine LAMA3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0297-Ag-1/ GM-Tg-hg-SE0297-Ag-2;
GM-Tg-rg-SE0297-Ag-1/ GM-Tg-rg-SE0297-Ag-2;
GM-Tg-mg-SE0297-Ag-1/ GM-Tg-mg-SE0297-Ag-2; GM-Tg-cynog-SE0297-Ag-1/ GM-Tg-cynog-SE0297-Ag-2; GM-Tg-felg-SE0297-Ag-1/ GM-Tg-felg-SE0297-Ag-2; GM-Tg-cang-SE0297-Ag-1/ GM-Tg-cang-SE0297-Ag-2; GM-Tg-bovg-SE0297-Ag-1/ GM-Tg-bovg-SE0297-Ag-2; GM-Tg-equg-SE0297-Ag-1/ GM-Tg-equg-SE0297-Ag-2 |
| Products Name | LAMA3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | LAMA3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LAMA3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.