Explore LAMA3 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]
| Target ID |
GM-SE0297
|
| Target Name |
LAMA3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3909
|
| Gene ID |
100336873 (Bos taurus), 101100161 (Felis catus), 16774 (Mus musculus), 307582 (Rattus norvegicus) 3909 (Homo sapiens), 480173 (Canis lupus familiaris), 701313 (Macaca mulatta), 791238 (Equus caballus)
|
| Target Alternative Names |
BM600,E170,Epiligrin 170 kDa subunit (E170),Epiligrin subunit alpha,JEB2A,JEB2B,JEB2C,Kalinin subunit alpha,LAMA3,LAMNA,LOCS,Lama3,Lama3B,Laminin subunit alpha-3,Laminin-5 subunit alpha,Laminin-6 subunit alpha,Laminin-7 subunit alpha,Nicein subunit alpha,[a]3B
|
| Uniprot Accession |
Q61789,Q16787
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Toxoplasmosis, Amoebiasis, Human papillomavirus infection, Pathways in cancer, Small cell lung cancer
|
| Gene Ensembl |
ENSBTAG00000027181, ENSMUSG00000024421, ENSG00000053747, ENSCAFG00845013821, ENSMMUG00000004321, ENSECAG00000021277
|
LAMA3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3909 | Pre-made Human LAMA3/E170/LOCS siRNA oligo Duplex | 3909 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo307582 | Pre-made Rat Lama3 siRNA oligo Duplex | 307582 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16774 | Pre-made Mouse Lama3/[a]3B/Lama3B siRNA oligo Duplex | 16774 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701313 | Pre-made Cynomolgus/Rhesus macaque LAMA3 siRNA oligo Duplex | 701313 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100161 | Pre-made Cat/Feline LAMA3 siRNA oligo Duplex | 101100161 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480173 | Pre-made Dog/Canine LAMA3 siRNA oligo Duplex | 480173 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336873 | Pre-made Bovines/Cattle LAMA3 siRNA oligo Duplex | 100336873 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo791238 | Pre-made Equine/Horse LAMA3 siRNA oligo Duplex | 791238 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LAMA3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0297-Ab | Human | Anti-Human LAMA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0297-Ab | Rat | Anti-Rat LAMA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0297-Ab | Mouse | Anti-Mouse LAMA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0297-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LAMA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0297-Ab | Cat/Feline | Anti-Cat/Feline LAMA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0297-Ab | Dog/Canine | Anti-Dog/Canine LAMA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0297-Ab | Bovines/Cattle | Anti-Bovines/Cattle LAMA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0297-Ab | Equine/Horse | Anti-Equine/Horse LAMA3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
LAMA3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0297-Ag | Human | Human LAMA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0297-Ag | Rat | Rat LAMA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0297-Ag | Mouse | Mouse LAMA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0297-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LAMA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0297-Ag | Cat/Feline | Cat/Feline LAMA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0297-Ag | Dog/Canine | Dog/Canine LAMA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0297-Ag | Bovines/Cattle | Bovines/Cattle LAMA3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0297-Ag | Equine/Horse | Equine/Horse LAMA3 recombinant protein | Mammalian cell | Detail |