Recombinant multi-species LAMA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LAMA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5830440B04,LAMA2,LAMM,Lama2,Laminin M chain,Laminin subunit alpha-2,Laminin-12 subunit alpha,Laminin-2 subunit alpha,Laminin-4 subunit alpha,MDC1A,Merosin heavy chain,dy,mKIAA4087,mer,merosin

Target products collectionGo to LAMA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0296-Ag-1/ GM-Tg-hg-SE0296-Ag-2 Human LAMA2 protein Human
GM-Tg-rg-SE0296-Ag-1/ GM-Tg-rg-SE0296-Ag-2 Rat LAMA2 protein Rat
GM-Tg-mg-SE0296-Ag-1/ GM-Tg-mg-SE0296-Ag-2 Mouse LAMA2 protein Mouse
GM-Tg-cynog-SE0296-Ag-1/ GM-Tg-cynog-SE0296-Ag-2 Cynomolgus/Rhesus macaque LAMA2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0296-Ag-1/ GM-Tg-felg-SE0296-Ag-2 Feline LAMA2 protein Feline
GM-Tg-cang-SE0296-Ag-1/ GM-Tg-cang-SE0296-Ag-2 Canine LAMA2 protein Canine
GM-Tg-bovg-SE0296-Ag-1/ GM-Tg-bovg-SE0296-Ag-2 Bovine LAMA2 protein Bovine
GM-Tg-equg-SE0296-Ag-1/ GM-Tg-equg-SE0296-Ag-2 Equine LAMA2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0296-Ag-1/ GM-Tg-hg-SE0296-Ag-2; GM-Tg-rg-SE0296-Ag-1/ GM-Tg-rg-SE0296-Ag-2;
GM-Tg-mg-SE0296-Ag-1/ GM-Tg-mg-SE0296-Ag-2; GM-Tg-cynog-SE0296-Ag-1/ GM-Tg-cynog-SE0296-Ag-2;
GM-Tg-felg-SE0296-Ag-1/ GM-Tg-felg-SE0296-Ag-2; GM-Tg-cang-SE0296-Ag-1/ GM-Tg-cang-SE0296-Ag-2;
GM-Tg-bovg-SE0296-Ag-1/ GM-Tg-bovg-SE0296-Ag-2; GM-Tg-equg-SE0296-Ag-1/ GM-Tg-equg-SE0296-Ag-2
Products Name LAMA2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LAMA2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LAMA2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.