Explore LAMA2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0296
|
| Target Name |
LAMA2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3908
|
| Gene ID |
100073067 (Equus caballus), 100138434 (Bos taurus), 100683420 (Canis lupus familiaris), 101092612 (Felis catus)
16773 (Mus musculus), 309368 (Rattus norvegicus), 3908 (Homo sapiens), 715394 (Macaca mulatta)
|
| Target Alternative Names |
5830440B04,LAMA2,LAMM,Lama2,Laminin M chain,Laminin subunit alpha-2,Laminin-12 subunit alpha,Laminin-2 subunit alpha,Laminin-4 subunit alpha,MDC1A,Merosin heavy chain,dy,mKIAA4087,mer,merosin
|
| Uniprot Accession |
Q60675,P24043
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Toxoplasmosis, Amoebiasis, Human papillomavirus infection, Pathways in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis
|
| Gene Ensembl |
ENSECAG00000023844, ENSBTAG00000010229, ENSCAFG00845001120, ENSMUSG00000019899, ENSG00000196569, ENSMMUG00000022136
|
LAMA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3908 | Pre-made Human LAMA2/LAMM/MDC1A siRNA oligo Duplex | 3908 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo309368 | Pre-made Rat Lama2 siRNA oligo Duplex | 309368 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16773 | Pre-made Mouse Lama2/dy/mer siRNA oligo Duplex | 16773 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715394 | Pre-made Cynomolgus/Rhesus macaque LAMA2 siRNA oligo Duplex | 715394 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092612 | Pre-made Cat/Feline LAMA2 siRNA oligo Duplex | 101092612 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100683420 | Pre-made Dog/Canine LAMA2 siRNA oligo Duplex | 100683420 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100138434 | Pre-made Bovines/Cattle LAMA2 siRNA oligo Duplex | 100138434 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073067 | Pre-made Equine/Horse LAMA2 siRNA oligo Duplex | 100073067 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LAMA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0296-Ab | Human | Anti-Human LAMA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0296-Ab | Rat | Anti-Rat LAMA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0296-Ab | Mouse | Anti-Mouse LAMA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0296-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LAMA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0296-Ab | Cat/Feline | Anti-Cat/Feline LAMA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0296-Ab | Dog/Canine | Anti-Dog/Canine LAMA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0296-Ab | Bovines/Cattle | Anti-Bovines/Cattle LAMA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0296-Ab | Equine/Horse | Anti-Equine/Horse LAMA2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
LAMA2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0296-Ag | Human | Human LAMA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0296-Ag | Rat | Rat LAMA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0296-Ag | Mouse | Mouse LAMA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0296-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LAMA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0296-Ag | Cat/Feline | Cat/Feline LAMA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0296-Ag | Dog/Canine | Dog/Canine LAMA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0296-Ag | Bovines/Cattle | Bovines/Cattle LAMA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0296-Ag | Equine/Horse | Equine/Horse LAMA2 recombinant protein | Mammalian cell | Detail |
