Recombinant multi-species GNS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GNS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2610016K11Rik,G6S,GNS,Glucosamine-6-sulfatase (G6S),Gns,N-acetylglucosamine-6-sulfatase

Target products collectionGo to GNS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0247-Ag-1/ GM-Tg-hg-SE0247-Ag-2 Human GNS protein Human
GM-Tg-rg-SE0247-Ag-1/ GM-Tg-rg-SE0247-Ag-2 Rat GNS protein Rat
GM-Tg-mg-SE0247-Ag-1/ GM-Tg-mg-SE0247-Ag-2 Mouse GNS protein Mouse
GM-Tg-cynog-SE0247-Ag-1/ GM-Tg-cynog-SE0247-Ag-2 Cynomolgus/Rhesus macaque GNS protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0247-Ag-1/ GM-Tg-felg-SE0247-Ag-2 Feline GNS protein Feline
GM-Tg-cang-SE0247-Ag-1/ GM-Tg-cang-SE0247-Ag-2 Canine GNS protein Canine
GM-Tg-bovg-SE0247-Ag-1/ GM-Tg-bovg-SE0247-Ag-2 Bovine GNS protein Bovine
GM-Tg-equg-SE0247-Ag-1/ GM-Tg-equg-SE0247-Ag-2 Equine GNS protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0247-Ag-1/ GM-Tg-hg-SE0247-Ag-2; GM-Tg-rg-SE0247-Ag-1/ GM-Tg-rg-SE0247-Ag-2;
GM-Tg-mg-SE0247-Ag-1/ GM-Tg-mg-SE0247-Ag-2; GM-Tg-cynog-SE0247-Ag-1/ GM-Tg-cynog-SE0247-Ag-2;
GM-Tg-felg-SE0247-Ag-1/ GM-Tg-felg-SE0247-Ag-2; GM-Tg-cang-SE0247-Ag-1/ GM-Tg-cang-SE0247-Ag-2;
GM-Tg-bovg-SE0247-Ag-1/ GM-Tg-bovg-SE0247-Ag-2; GM-Tg-equg-SE0247-Ag-1/ GM-Tg-equg-SE0247-Ag-2
Products Name GNS protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GNS
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GNS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.