Explore GNS gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0247
|
| Target Name |
GNS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2799
|
| Gene ID |
100034131 (Equus caballus), 101088174 (Felis catus), 2799 (Homo sapiens), 299825 (Rattus norvegicus)
474429 (Canis lupus familiaris), 512444 (Bos taurus), 717500 (Macaca mulatta), 75612 (Mus musculus)
|
| Target Alternative Names |
2610016K11Rik,G6S,GNS,Glucosamine-6-sulfatase (G6S),Gns,N-acetylglucosamine-6-sulfatase
|
| Uniprot Accession |
P15586,Q1LZH9,Q8BFR4
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Metabolic pathways, Lysosome, Glycosaminoglycan degradation
|
| Gene Ensembl |
ENSECAG00000023318, ENSG00000135677, ENSCAFG00845011574, ENSBTAG00000017465, ENSMMUG00000006481, ENSMUSG00000034707
|
Pre-made viral vector of GNS cDNA Clones/ORF Plasmid
GNS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2799 | Pre-made Human GNS/G6S siRNA oligo Duplex | 2799 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo299825 | Pre-made Rat Gns siRNA oligo Duplex | 299825 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo75612 | Pre-made Mouse Gns/G6S/2610016K11Rik siRNA oligo Duplex | 75612 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717500 | Pre-made Cynomolgus/Rhesus macaque GNS siRNA oligo Duplex | 717500 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088174 | Pre-made Cat/Feline GNS siRNA oligo Duplex | 101088174 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474429 | Pre-made Dog/Canine GNS siRNA oligo Duplex | 474429 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512444 | Pre-made Bovines/Cattle GNS/G6S siRNA oligo Duplex | 512444 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034131 | Pre-made Equine/Horse GNS/G6S siRNA oligo Duplex | 100034131 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GNS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0247-Ab | Human | Anti-Human GNS monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0247-Ab | Rat | Anti-Rat GNS monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0247-Ab | Mouse | Anti-Mouse GNS monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0247-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GNS monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0247-Ab | Cat/Feline | Anti-Cat/Feline GNS monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0247-Ab | Dog/Canine | Anti-Dog/Canine GNS monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE0247-Ab | Bovines/Cattle | Anti-Bovines/Cattle GNS monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0247-Ab | Equine/Horse | Anti-Equine/Horse GNS monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GNS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0247-Ag | Human | Human GNS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0247-Ag | Rat | Rat GNS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0247-Ag | Mouse | Mouse GNS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0247-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GNS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0247-Ag | Cat/Feline | Cat/Feline GNS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0247-Ag | Dog/Canine | Dog/Canine GNS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0247-Ag | Bovines/Cattle | Bovines/Cattle GNS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0247-Ag | Equine/Horse | Equine/Horse GNS recombinant protein | Mammalian cell | Detail |
