Recombinant multi-species 45934/POU5F1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine 45934/POU5F1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
The Alternative Names of target: 45934,NF-A3,OCT3,OCT3/4,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-3/4,Oct-4,Oct3,Oct3/4,Oct4,Octamer-binding protein 3 (Oct-3),Octamer-binding protein 4 (Oct-4),Octamer-binding transcription factor 3 (OTF-3),Otf-3,Otf-4,Otf3,Otf3-rs7,Otf3g,Otf4,POU domain,POU5F1,Pou5f1,class 5,oct-3,oct-4,transcription factor 1

Target products collectionGo to 45934/POU5F1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9765-Ag-1/ GM-Tg-hg-IP9765-Ag-2 Human 45934/POU5F1 protein Human
GM-Tg-rg-IP9765-Ag-1/ GM-Tg-rg-IP9765-Ag-2 Rat 45934/POU5F1 protein Rat
GM-Tg-mg-IP9765-Ag-1/ GM-Tg-mg-IP9765-Ag-2 Mouse 45934/POU5F1 protein Mouse
GM-Tg-cynog-IP9765-Ag-1/ GM-Tg-cynog-IP9765-Ag-2 Cynomolgus/Rhesus macaque 45934/POU5F1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9765-Ag-1/ GM-Tg-felg-IP9765-Ag-2 Feline 45934/POU5F1 protein Feline
GM-Tg-cang-IP9765-Ag-1/ GM-Tg-cang-IP9765-Ag-2 Canine 45934/POU5F1 protein Canine
GM-Tg-bovg-IP9765-Ag-1/ GM-Tg-bovg-IP9765-Ag-2 Bovine 45934/POU5F1 protein Bovine
GM-Tg-equg-IP9765-Ag-1/ GM-Tg-equg-IP9765-Ag-2 Equine 45934/POU5F1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9765-Ag-1/ GM-Tg-hg-IP9765-Ag-2; GM-Tg-rg-IP9765-Ag-1/ GM-Tg-rg-IP9765-Ag-2;
GM-Tg-mg-IP9765-Ag-1/ GM-Tg-mg-IP9765-Ag-2; GM-Tg-cynog-IP9765-Ag-1/ GM-Tg-cynog-IP9765-Ag-2;
GM-Tg-felg-IP9765-Ag-1/ GM-Tg-felg-IP9765-Ag-2; GM-Tg-cang-IP9765-Ag-1/ GM-Tg-cang-IP9765-Ag-2;
GM-Tg-bovg-IP9765-Ag-1/ GM-Tg-bovg-IP9765-Ag-2; GM-Tg-equg-IP9765-Ag-1/ GM-Tg-equg-IP9765-Ag-2
Products Name 45934/POU5F1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name 45934/POU5F1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine 45934/POU5F1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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