Recombinant multi-species 45934/POU5F1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine 45934/POU5F1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
The Alternative Names of target: 45934,NF-A3,OCT3,OCT3/4,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-3/4,Oct-4,Oct3,Oct3/4,Oct4,Octamer-binding protein 3 (Oct-3),Octamer-binding protein 4 (Oct-4),Octamer-binding transcription factor 3 (OTF-3),Otf-3,Otf-4,Otf3,Otf3-rs7,Otf3g,Otf4,POU domain,POU5F1,Pou5f1,class 5,oct-3,oct-4,transcription factor 1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9765-Ag-1/ GM-Tg-hg-IP9765-Ag-2 | Human 45934/POU5F1 protein | Human |
| GM-Tg-rg-IP9765-Ag-1/ GM-Tg-rg-IP9765-Ag-2 | Rat 45934/POU5F1 protein | Rat |
| GM-Tg-mg-IP9765-Ag-1/ GM-Tg-mg-IP9765-Ag-2 | Mouse 45934/POU5F1 protein | Mouse |
| GM-Tg-cynog-IP9765-Ag-1/ GM-Tg-cynog-IP9765-Ag-2 | Cynomolgus/Rhesus macaque 45934/POU5F1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9765-Ag-1/ GM-Tg-felg-IP9765-Ag-2 | Feline 45934/POU5F1 protein | Feline |
| GM-Tg-cang-IP9765-Ag-1/ GM-Tg-cang-IP9765-Ag-2 | Canine 45934/POU5F1 protein | Canine |
| GM-Tg-bovg-IP9765-Ag-1/ GM-Tg-bovg-IP9765-Ag-2 | Bovine 45934/POU5F1 protein | Bovine |
| GM-Tg-equg-IP9765-Ag-1/ GM-Tg-equg-IP9765-Ag-2 | Equine 45934/POU5F1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9765-Ag-1/ GM-Tg-hg-IP9765-Ag-2;
GM-Tg-rg-IP9765-Ag-1/ GM-Tg-rg-IP9765-Ag-2;
GM-Tg-mg-IP9765-Ag-1/ GM-Tg-mg-IP9765-Ag-2; GM-Tg-cynog-IP9765-Ag-1/ GM-Tg-cynog-IP9765-Ag-2; GM-Tg-felg-IP9765-Ag-1/ GM-Tg-felg-IP9765-Ag-2; GM-Tg-cang-IP9765-Ag-1/ GM-Tg-cang-IP9765-Ag-2; GM-Tg-bovg-IP9765-Ag-1/ GM-Tg-bovg-IP9765-Ag-2; GM-Tg-equg-IP9765-Ag-1/ GM-Tg-equg-IP9765-Ag-2 |
| Products Name | 45934/POU5F1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | 45934/POU5F1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine 45934/POU5F1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.