Explore 45934/POU5F1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
| Target ID |
GM-IP9765
|
| Target Name |
45934/POU5F1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5460
|
| Gene ID |
100050785 (Equus caballus), 100174788 (Felis catus), 119881658 (Canis lupus familiaris), 18999 (Mus musculus) 282316 (Bos taurus), 294562 (Rattus norvegicus), 5460 (Homo sapiens), 714760 (Macaca mulatta)
|
| Target Alternative Names |
45934,NF-A3,OCT3,OCT3/4,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-3/4,Oct-4,Oct3,Oct3/4,Oct4,Octamer-binding protein 3 (Oct-3),Octamer-binding protein 4 (Oct-4),Octamer-binding transcription factor 3 (OTF-3),Otf-3,Otf-4,Otf3,Otf3-rs7,Otf3g,Otf4,POU domain,POU5F1,Pou5f1,class 5,oct-3,oct-4,transcription factor 1
|
| Uniprot Accession |
P20263,O97552,Q01860,Q5TM49
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000008967, ENSMUSG00000024406, ENSBTAG00000021111, ENSG00000204531, ENSMMUG00000015688
|
Pre-made viral vector of 45934/POU5F1 cDNA Clones/ORF Plasmid
45934/POU5F1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5460 | Pre-made Human POU5F1/OCT3/OCT4 siRNA oligo Duplex | 5460 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294562 | Pre-made Rat Pou5f1 siRNA oligo Duplex | 294562 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18999 | Pre-made Mouse Pou5f1/Oct3/Oct4 siRNA oligo Duplex | 18999 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714760 | Pre-made Cynomolgus/Rhesus macaque POU5F1/OCT3/OCT4 siRNA oligo Duplex | 714760 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100174788 | Pre-made Cat/Feline POU5F1/Oct4 siRNA oligo Duplex | 100174788 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119881658 | Pre-made Dog/Canine POU5F1 siRNA oligo Duplex | 119881658 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282316 | Pre-made Bovines/Cattle POU5F1/OCT3/OCT4 siRNA oligo Duplex | 282316 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050785 | Pre-made Equine/Horse POU5F1 siRNA oligo Duplex | 100050785 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
45934/POU5F1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9765-Ab | Human | Anti-Human 45934/POU5F1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9765-Ab | Rat | Anti-Rat 45934/POU5F1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9765-Ab | Mouse | Anti-Mouse 45934/POU5F1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9765-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque 45934/POU5F1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9765-Ab | Cat/Feline | Anti-Cat/Feline 45934/POU5F1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9765-Ab | Dog/Canine | Anti-Dog/Canine 45934/POU5F1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9765-Ab | Bovines/Cattle | Anti-Bovines/Cattle 45934/POU5F1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9765-Ab | Equine/Horse | Anti-Equine/Horse 45934/POU5F1 monoclonal antibody | mab | | Detail |
45934/POU5F1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9765-Ag | Human | Human 45934/POU5F1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9765-Ag | Rat | Rat 45934/POU5F1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9765-Ag | Mouse | Mouse 45934/POU5F1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9765-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque 45934/POU5F1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9765-Ag | Cat/Feline | Cat/Feline 45934/POU5F1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9765-Ag | Dog/Canine | Dog/Canine 45934/POU5F1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9765-Ag | Bovines/Cattle | Bovines/Cattle 45934/POU5F1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9765-Ag | Equine/Horse | Equine/Horse 45934/POU5F1 recombinant protein | Mammalian cell | Detail |