Recombinant multi-species SMOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012]
The Alternative Names of target: B130066H01Rik,C20orf16,PAO,PAO-1,PAO1,PAOH,PAOH1,PAOh1,PAOh1),Polyamine oxidase 1 (PAO-1,SMO,SMOX,Smox,Spermine oxidase

Target products collectionGo to SMOX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9726-Ag-1/ GM-Tg-hg-IP9726-Ag-2 Human SMOX protein Human
GM-Tg-rg-IP9726-Ag-1/ GM-Tg-rg-IP9726-Ag-2 Rat SMOX protein Rat
GM-Tg-mg-IP9726-Ag-1/ GM-Tg-mg-IP9726-Ag-2 Mouse SMOX protein Mouse
GM-Tg-cynog-IP9726-Ag-1/ GM-Tg-cynog-IP9726-Ag-2 Cynomolgus/Rhesus macaque SMOX protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9726-Ag-1/ GM-Tg-felg-IP9726-Ag-2 Feline SMOX protein Feline
GM-Tg-cang-IP9726-Ag-1/ GM-Tg-cang-IP9726-Ag-2 Canine SMOX protein Canine
GM-Tg-bovg-IP9726-Ag-1/ GM-Tg-bovg-IP9726-Ag-2 Bovine SMOX protein Bovine
GM-Tg-equg-IP9726-Ag-1/ GM-Tg-equg-IP9726-Ag-2 Equine SMOX protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9726-Ag-1/ GM-Tg-hg-IP9726-Ag-2; GM-Tg-rg-IP9726-Ag-1/ GM-Tg-rg-IP9726-Ag-2;
GM-Tg-mg-IP9726-Ag-1/ GM-Tg-mg-IP9726-Ag-2; GM-Tg-cynog-IP9726-Ag-1/ GM-Tg-cynog-IP9726-Ag-2;
GM-Tg-felg-IP9726-Ag-1/ GM-Tg-felg-IP9726-Ag-2; GM-Tg-cang-IP9726-Ag-1/ GM-Tg-cang-IP9726-Ag-2;
GM-Tg-bovg-IP9726-Ag-1/ GM-Tg-bovg-IP9726-Ag-2; GM-Tg-equg-IP9726-Ag-1/ GM-Tg-equg-IP9726-Ag-2
Products Name SMOX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SMOX
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMOX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.