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Target
sublocation: Introcelluar Protein.
Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012]
| Target ID |
GM-IP9726
|
| Target Name |
SMOX
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
54498
|
| Gene ID |
100052311 (Equus caballus), 101084867 (Felis catus), 228608 (Mus musculus), 308652 (Rattus norvegicus) 485787 (Canis lupus familiaris), 527211 (Bos taurus), 54498 (Homo sapiens), 718761 (Macaca mulatta)
|
| Target Alternative Names |
B130066H01Rik,C20orf16,PAO,PAO-1,PAO1,PAOH,PAOH1,PAOh1,PAOh1),Polyamine oxidase 1 (PAO-1,SMO,SMOX,Smox,Spermine oxidase
|
| Uniprot Accession |
Q99K82,Q9NWM0
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000005905, ENSMUSG00000027333, ENSCAFG00845013771, ENSBTAG00000001112, ENSG00000088826, ENSMMUG00000020912
|
Pre-made viral vector of SMOX cDNA Clones/ORF Plasmid
SMOX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo54498 | Pre-made Human SMOX/PAO/SMO siRNA oligo Duplex | 54498 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308652 | Pre-made Rat Smox siRNA oligo Duplex | 308652 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo228608 | Pre-made Mouse Smox/PAO/SMO siRNA oligo Duplex | 228608 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718761 | Pre-made Cynomolgus/Rhesus macaque SMOX siRNA oligo Duplex | 718761 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084867 | Pre-made Cat/Feline SMOX siRNA oligo Duplex | 101084867 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485787 | Pre-made Dog/Canine SMOX siRNA oligo Duplex | 485787 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo527211 | Pre-made Bovines/Cattle SMOX siRNA oligo Duplex | 527211 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052311 | Pre-made Equine/Horse SMOX siRNA oligo Duplex | 100052311 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SMOX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9726-Ab | Human | Anti-Human SMOX monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9726-Ab | Rat | Anti-Rat SMOX monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9726-Ab | Mouse | Anti-Mouse SMOX monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9726-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SMOX monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9726-Ab | Cat/Feline | Anti-Cat/Feline SMOX monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9726-Ab | Dog/Canine | Anti-Dog/Canine SMOX monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9726-Ab | Bovines/Cattle | Anti-Bovines/Cattle SMOX monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9726-Ab | Equine/Horse | Anti-Equine/Horse SMOX monoclonal antibody | mab | | Detail |
SMOX recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9726-Ag | Human | Human SMOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9726-Ag | Rat | Rat SMOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9726-Ag | Mouse | Mouse SMOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9726-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SMOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9726-Ag | Cat/Feline | Cat/Feline SMOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9726-Ag | Dog/Canine | Dog/Canine SMOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9726-Ag | Bovines/Cattle | Bovines/Cattle SMOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9726-Ag | Equine/Horse | Equine/Horse SMOX recombinant protein | Mammalian cell | Detail |