Recombinant multi-species PRKAG3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRKAG3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5'-AMP-activated protein kinase subunit gamma-3,AMPK gamma3,AMPK subunit gamma-3,AMPKG3,AMPKg3L,AMPKg3S,Amkg3,Ampkg3,PRKAG3,Prkag3,SMGMQTL

Target products collectionGo to PRKAG3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9640-Ag-1/ GM-Tg-hg-IP9640-Ag-2 Human PRKAG3 protein Human
GM-Tg-rg-IP9640-Ag-1/ GM-Tg-rg-IP9640-Ag-2 Rat PRKAG3 protein Rat
GM-Tg-mg-IP9640-Ag-1/ GM-Tg-mg-IP9640-Ag-2 Mouse PRKAG3 protein Mouse
GM-Tg-cynog-IP9640-Ag-1/ GM-Tg-cynog-IP9640-Ag-2 Cynomolgus/Rhesus macaque PRKAG3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9640-Ag-1/ GM-Tg-felg-IP9640-Ag-2 Feline PRKAG3 protein Feline
GM-Tg-cang-IP9640-Ag-1/ GM-Tg-cang-IP9640-Ag-2 Canine PRKAG3 protein Canine
GM-Tg-bovg-IP9640-Ag-1/ GM-Tg-bovg-IP9640-Ag-2 Bovine PRKAG3 protein Bovine
GM-Tg-equg-IP9640-Ag-1/ GM-Tg-equg-IP9640-Ag-2 Equine PRKAG3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9640-Ag-1/ GM-Tg-hg-IP9640-Ag-2; GM-Tg-rg-IP9640-Ag-1/ GM-Tg-rg-IP9640-Ag-2;
GM-Tg-mg-IP9640-Ag-1/ GM-Tg-mg-IP9640-Ag-2; GM-Tg-cynog-IP9640-Ag-1/ GM-Tg-cynog-IP9640-Ag-2;
GM-Tg-felg-IP9640-Ag-1/ GM-Tg-felg-IP9640-Ag-2; GM-Tg-cang-IP9640-Ag-1/ GM-Tg-cang-IP9640-Ag-2;
GM-Tg-bovg-IP9640-Ag-1/ GM-Tg-bovg-IP9640-Ag-2; GM-Tg-equg-IP9640-Ag-1/ GM-Tg-equg-IP9640-Ag-2
Products Name PRKAG3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PRKAG3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRKAG3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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