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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP9640
|
| Target Name |
PRKAG3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
53632
|
| Gene ID |
100034099 (Equus caballus), 101092204 (Felis catus), 241113 (Mus musculus), 301518 (Rattus norvegicus) 488526 (Canis lupus familiaris), 511961 (Bos taurus), 53632 (Homo sapiens), 702782 (Macaca mulatta)
|
| Target Alternative Names |
5'-AMP-activated protein kinase subunit gamma-3,AMPK gamma3,AMPK subunit gamma-3,AMPKG3,AMPKg3L,AMPKg3S,Amkg3,Ampkg3,PRKAG3,Prkag3,SMGMQTL
|
| Uniprot Accession |
Q8BGM7,Q2LL38,Q9UGI9
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000002430, ENSMUSG00000006542, ENSCAFG00845028465, ENSBTAG00000013492, ENSG00000115592, ENSMMUG00000021877
|
Pre-made viral vector of PRKAG3 cDNA Clones/ORF Plasmid
PRKAG3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo53632 | Pre-made Human PRKAG3/AMPKG3/SMGMQTL siRNA oligo Duplex | 53632 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301518 | Pre-made Rat Prkag3/Ampkg3 siRNA oligo Duplex | 301518 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo241113 | Pre-made Mouse Prkag3/Amkg3/Ampkg3 siRNA oligo Duplex | 241113 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702782 | Pre-made Cynomolgus/Rhesus macaque PRKAG3 siRNA oligo Duplex | 702782 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092204 | Pre-made Cat/Feline PRKAG3 siRNA oligo Duplex | 101092204 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488526 | Pre-made Dog/Canine PRKAG3 siRNA oligo Duplex | 488526 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511961 | Pre-made Bovines/Cattle PRKAG3 siRNA oligo Duplex | 511961 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034099 | Pre-made Equine/Horse PRKAG3 siRNA oligo Duplex | 100034099 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRKAG3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9640-Ab | Human | Anti-Human PRKAG3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9640-Ab | Rat | Anti-Rat PRKAG3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9640-Ab | Mouse | Anti-Mouse PRKAG3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9640-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRKAG3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9640-Ab | Cat/Feline | Anti-Cat/Feline PRKAG3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9640-Ab | Dog/Canine | Anti-Dog/Canine PRKAG3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9640-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRKAG3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9640-Ab | Equine/Horse | Anti-Equine/Horse PRKAG3 monoclonal antibody | mab | | Detail |
PRKAG3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9640-Ag | Human | Human PRKAG3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9640-Ag | Rat | Rat PRKAG3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9640-Ag | Mouse | Mouse PRKAG3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9640-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRKAG3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9640-Ag | Cat/Feline | Cat/Feline PRKAG3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9640-Ag | Dog/Canine | Dog/Canine PRKAG3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9640-Ag | Bovines/Cattle | Bovines/Cattle PRKAG3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9640-Ag | Equine/Horse | Equine/Horse PRKAG3 recombinant protein | Mammalian cell | Detail |