Recombinant multi-species PKLR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKLR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CNSHA2,PK1,PKL,PKLR,PKRL,Pk-1,Pk1,Pklg,Pklr,Pyruvate kinase 1,Pyruvate kinase PKLR,Pyruvate kinase isozymes L/R,R-PK,R-type/L-type pyruvate kinase,RPK,Red cell/liver pyruvate kinase

Target products collectionGo to PKLR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9614-Ag-1/ GM-Tg-hg-IP9614-Ag-2 Human PKLR protein Human
GM-Tg-rg-IP9614-Ag-1/ GM-Tg-rg-IP9614-Ag-2 Rat PKLR protein Rat
GM-Tg-mg-IP9614-Ag-1/ GM-Tg-mg-IP9614-Ag-2 Mouse PKLR protein Mouse
GM-Tg-cynog-IP9614-Ag-1/ GM-Tg-cynog-IP9614-Ag-2 Cynomolgus/Rhesus macaque PKLR protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9614-Ag-1/ GM-Tg-felg-IP9614-Ag-2 Feline PKLR protein Feline
GM-Tg-cang-IP9614-Ag-1/ GM-Tg-cang-IP9614-Ag-2 Canine PKLR protein Canine
GM-Tg-bovg-IP9614-Ag-1/ GM-Tg-bovg-IP9614-Ag-2 Bovine PKLR protein Bovine
GM-Tg-equg-IP9614-Ag-1/ GM-Tg-equg-IP9614-Ag-2 Equine PKLR protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9614-Ag-1/ GM-Tg-hg-IP9614-Ag-2; GM-Tg-rg-IP9614-Ag-1/ GM-Tg-rg-IP9614-Ag-2;
GM-Tg-mg-IP9614-Ag-1/ GM-Tg-mg-IP9614-Ag-2; GM-Tg-cynog-IP9614-Ag-1/ GM-Tg-cynog-IP9614-Ag-2;
GM-Tg-felg-IP9614-Ag-1/ GM-Tg-felg-IP9614-Ag-2; GM-Tg-cang-IP9614-Ag-1/ GM-Tg-cang-IP9614-Ag-2;
GM-Tg-bovg-IP9614-Ag-1/ GM-Tg-bovg-IP9614-Ag-2; GM-Tg-equg-IP9614-Ag-1/ GM-Tg-equg-IP9614-Ag-2
Products Name PKLR protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PKLR
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKLR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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