PKLR Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PKLR gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Target ID	GM-IP9614
Target Name	PKLR
Gene Group ldentifer （Target Gene ID in Homo species)	5313
Gene ID	100063608 (Equus caballus), 101088459 (Felis catus), 18770 (Mus musculus), 24651 (Rattus norvegicus) 490425 (Canis lupus familiaris), 5313 (Homo sapiens), 539579 (Bos taurus), 719152 (Macaca mulatta)
Target Alternative Names	CNSHA2,PK1,PKL,PKLR,PKRL,Pk-1,Pk1,Pklg,Pklr,Pyruvate kinase 1,Pyruvate kinase PKLR,Pyruvate kinase isozymes L/R,R-PK,R-type/L-type pyruvate kinase,RPK,Red cell/liver pyruvate kinase
Uniprot Accession	P53657,P12928,Q29536,P30613
Protein Sub-location	Introcelluar Protein
Category	Life Science Target
Gene Ensembl	ENSECAG00000013836, ENSMUSG00000041237, ENSCAFG00845012059, ENSG00000143627, ENSBTAG00000017056, ENSMMUG00000023143

Pre-made viral vector of PKLR cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP005291	Human PKLR/PK1/PKL Lentivirus plasmid	NM_000298.5	5313	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAD000005	Human PKLR/PK1/PKL Adenovirus plasmid	NM_000298.5	5313	Human	Adenovirus plasmid	Null	3xflag (C-Terminal)	CMV	Detail
pGMAAV000002	Human PKLR/PK1/PKL Adeno-associate virus(AAV) plasmid	NM_000298.5	5313	Human	Adeno-associate virus(AAV) plasmid	GFP	3xflag (C-Terminal)	CMV	Detail
pGMPC001421	Human PKLR/PK1/PKL Mammalian (Non-Viral Vector) plasmid	NM_000298.6	5313	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMLP005291	Human PKLR/PK1/PKL Lentivirus particle	NM_000298.5	5313	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAD000005	Human PKLR/PK1/PKL Adenovirus particle	NM_000298.5	5313	Human	Adenovirus particle	Null	3xflag (C-Terminal)	CMV	Detail
vGMAAV000002	Human PKLR/PK1/PKL Adeno-associate virus(AAV) particle	NM_000298.5	5313	Human	Adeno-associate virus(AAV) particle	GFP	3xflag (C-Terminal)	CMV	Detail

PKLR siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo5313	Pre-made Human PKLR/PK1/PKL siRNA oligo Duplex	5313	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo24651	Pre-made Rat Pklr/PK1/PKL siRNA oligo Duplex	24651	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo18770	Pre-made Mouse Pklr/Pk1/Pk-1 siRNA oligo Duplex	18770	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo719152	Pre-made Cynomolgus/Rhesus macaque PKLR siRNA oligo Duplex	719152	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101088459	Pre-made Cat/Feline PKLR siRNA oligo Duplex	101088459	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo490425	Pre-made Dog/Canine PKLR siRNA oligo Duplex	490425	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo539579	Pre-made Bovines/Cattle PKLR siRNA oligo Duplex	539579	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100063608	Pre-made Equine/Horse PKLR siRNA oligo Duplex	100063608	Equine/Horse	In-vitro grade; in-vivo grade	Detail

PKLR antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-IP9614-Ab	Human	Anti-Human PKLR monoclonal antibody	mab	Detail
GM-Tg-rg-IP9614-Ab	Rat	Anti-Rat PKLR monoclonal antibody	mab	Detail
GM-Tg-mg-IP9614-Ab	Mouse	Anti-Mouse PKLR monoclonal antibody	mab	Detail
GM-Tg-cynog-IP9614-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque PKLR monoclonal antibody	mab	Detail
GM-Tg-felg-IP9614-Ab	Cat/Feline	Anti-Cat/Feline PKLR monoclonal antibody	mab	Detail
GM-Tg-cang-IP9614-Ab	Dog/Canine	Anti-Dog/Canine PKLR monoclonal antibody	mab	Detail
GM-Tg-bovg-IP9614-Ab	Bovines/Cattle	Anti-Bovines/Cattle PKLR monoclonal antibody	mab	Detail
GM-Tg-equg-IP9614-Ab	Equine/Horse	Anti-Equine/Horse PKLR monoclonal antibody	mab	Detail

PKLR recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP9614-Ag	Human	Human PKLR recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP9614-Ag	Rat	Rat PKLR recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP9614-Ag	Mouse	Mouse PKLR recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-IP9614-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque PKLR recombinant protein	Mammalian cell	Detail
GM-Tg-felg-IP9614-Ag	Cat/Feline	Cat/Feline PKLR recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP9614-Ag	Dog/Canine	Dog/Canine PKLR recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP9614-Ag	Bovines/Cattle	Bovines/Cattle PKLR recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP9614-Ag	Equine/Horse	Equine/Horse PKLR recombinant protein	Mammalian cell	Detail