Recombinant multi-species PGK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
The Alternative Names of target: Cell migration-inducing gene 10 protein,HEL-S-68p,MIG10,PGK,PGK1,PGKA,Pgk,Pgk-1,Pgk1,Phosphoglycerate kinase 1,Primer recognition protein 2 (PRP 2)

Target products collectionGo to PGK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9584-Ag-1/ GM-Tg-hg-IP9584-Ag-2 Human PGK1 protein Human
GM-Tg-rg-IP9584-Ag-1/ GM-Tg-rg-IP9584-Ag-2 Rat PGK1 protein Rat
GM-Tg-mg-IP9584-Ag-1/ GM-Tg-mg-IP9584-Ag-2 Mouse PGK1 protein Mouse
GM-Tg-cynog-IP9584-Ag-1/ GM-Tg-cynog-IP9584-Ag-2 Cynomolgus/Rhesus macaque PGK1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9584-Ag-1/ GM-Tg-felg-IP9584-Ag-2 Feline PGK1 protein Feline
GM-Tg-cang-IP9584-Ag-1/ GM-Tg-cang-IP9584-Ag-2 Canine PGK1 protein Canine
GM-Tg-bovg-IP9584-Ag-1/ GM-Tg-bovg-IP9584-Ag-2 Bovine PGK1 protein Bovine
GM-Tg-equg-IP9584-Ag-1/ GM-Tg-equg-IP9584-Ag-2 Equine PGK1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9584-Ag-1/ GM-Tg-hg-IP9584-Ag-2; GM-Tg-rg-IP9584-Ag-1/ GM-Tg-rg-IP9584-Ag-2;
GM-Tg-mg-IP9584-Ag-1/ GM-Tg-mg-IP9584-Ag-2; GM-Tg-cynog-IP9584-Ag-1/ GM-Tg-cynog-IP9584-Ag-2;
GM-Tg-felg-IP9584-Ag-1/ GM-Tg-felg-IP9584-Ag-2; GM-Tg-cang-IP9584-Ag-1/ GM-Tg-cang-IP9584-Ag-2;
GM-Tg-bovg-IP9584-Ag-1/ GM-Tg-bovg-IP9584-Ag-2; GM-Tg-equg-IP9584-Ag-1/ GM-Tg-equg-IP9584-Ag-2
Products Name PGK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PGK1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.