Recombinant multi-species PGK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
The Alternative Names of target: Cell migration-inducing gene 10 protein,HEL-S-68p,MIG10,PGK,PGK1,PGKA,Pgk,Pgk-1,Pgk1,Phosphoglycerate kinase 1,Primer recognition protein 2 (PRP 2)
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9584-Ag-1/ GM-Tg-hg-IP9584-Ag-2 | Human PGK1 protein | Human |
| GM-Tg-rg-IP9584-Ag-1/ GM-Tg-rg-IP9584-Ag-2 | Rat PGK1 protein | Rat |
| GM-Tg-mg-IP9584-Ag-1/ GM-Tg-mg-IP9584-Ag-2 | Mouse PGK1 protein | Mouse |
| GM-Tg-cynog-IP9584-Ag-1/ GM-Tg-cynog-IP9584-Ag-2 | Cynomolgus/Rhesus macaque PGK1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9584-Ag-1/ GM-Tg-felg-IP9584-Ag-2 | Feline PGK1 protein | Feline |
| GM-Tg-cang-IP9584-Ag-1/ GM-Tg-cang-IP9584-Ag-2 | Canine PGK1 protein | Canine |
| GM-Tg-bovg-IP9584-Ag-1/ GM-Tg-bovg-IP9584-Ag-2 | Bovine PGK1 protein | Bovine |
| GM-Tg-equg-IP9584-Ag-1/ GM-Tg-equg-IP9584-Ag-2 | Equine PGK1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9584-Ag-1/ GM-Tg-hg-IP9584-Ag-2;
GM-Tg-rg-IP9584-Ag-1/ GM-Tg-rg-IP9584-Ag-2;
GM-Tg-mg-IP9584-Ag-1/ GM-Tg-mg-IP9584-Ag-2; GM-Tg-cynog-IP9584-Ag-1/ GM-Tg-cynog-IP9584-Ag-2; GM-Tg-felg-IP9584-Ag-1/ GM-Tg-felg-IP9584-Ag-2; GM-Tg-cang-IP9584-Ag-1/ GM-Tg-cang-IP9584-Ag-2; GM-Tg-bovg-IP9584-Ag-1/ GM-Tg-bovg-IP9584-Ag-2; GM-Tg-equg-IP9584-Ag-1/ GM-Tg-equg-IP9584-Ag-2 |
| Products Name | PGK1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PGK1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.