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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
| Target ID |
GM-IP9584
|
| Target Name |
PGK1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5230
|
| Gene ID |
100072656 (Equus caballus), 101087208 (Felis catus), 18655 (Mus musculus), 24644 (Rattus norvegicus) 480964 (Canis lupus familiaris), 507476 (Bos taurus), 5230 (Homo sapiens), 706325 (Macaca mulatta)
|
| Target Alternative Names |
Cell migration-inducing gene 10 protein,HEL-S-68p,MIG10,PGK,PGK1,PGKA,Pgk,Pgk-1,Pgk1,Phosphoglycerate kinase 1,Primer recognition protein 2 (PRP 2)
|
| Uniprot Accession |
P00559,P09411,P16617,Q3T0P6,P00558
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000014984, ENSMUSG00000062070, ENSCAFG00845020758, ENSBTAG00000000894, ENSG00000102144, ENSMMUG00000012874
|
Pre-made viral vector of PGK1 cDNA Clones/ORF Plasmid
PGK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5230 | Pre-made Human PGK1/PGKA/MIG10 siRNA oligo Duplex | 5230 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24644 | Pre-made Rat Pgk1/Pgk siRNA oligo Duplex | 24644 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18655 | Pre-made Mouse Pgk1/Pgk-1 siRNA oligo Duplex | 18655 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706325 | Pre-made Cynomolgus/Rhesus macaque PGK1 siRNA oligo Duplex | 706325 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087208 | Pre-made Cat/Feline PGK1 siRNA oligo Duplex | 101087208 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480964 | Pre-made Dog/Canine PGK1 siRNA oligo Duplex | 480964 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507476 | Pre-made Bovines/Cattle PGK1 siRNA oligo Duplex | 507476 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072656 | Pre-made Equine/Horse PGK1/PGK siRNA oligo Duplex | 100072656 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PGK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9584-Ab | Human | Anti-Human PGK1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9584-Ab | Rat | Anti-Rat PGK1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9584-Ab | Mouse | Anti-Mouse PGK1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9584-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PGK1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9584-Ab | Cat/Feline | Anti-Cat/Feline PGK1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9584-Ab | Dog/Canine | Anti-Dog/Canine PGK1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9584-Ab | Bovines/Cattle | Anti-Bovines/Cattle PGK1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9584-Ab | Equine/Horse | Anti-Equine/Horse PGK1 monoclonal antibody | mab | | Detail |
PGK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9584-Ag | Human | Human PGK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9584-Ag | Rat | Rat PGK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9584-Ag | Mouse | Mouse PGK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9584-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PGK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9584-Ag | Cat/Feline | Cat/Feline PGK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9584-Ag | Dog/Canine | Dog/Canine PGK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9584-Ag | Bovines/Cattle | Bovines/Cattle PGK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9584-Ag | Equine/Horse | Equine/Horse PGK1 recombinant protein | Mammalian cell | Detail |