Recombinant multi-species SIRT6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SIRT6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
The Alternative Names of target: 2810449N18Rik,NAD-dependent protein deacetylase sirtuin-6,NAD-dependent protein deacylase sirtuin-6,Protein mono-ADP-ribosyltransferase sirtuin-6,Regulatory protein SIR2 homolog 6 (hSIRT6),SIR2-like protein 6,SIR2L6,SIRT6,Sir2l6,Sirt6,hSIRT6,mSIRT6

Target products collectionGo to SIRT6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9473-Ag-1/ GM-Tg-hg-IP9473-Ag-2 Human SIRT6 protein Human
GM-Tg-rg-IP9473-Ag-1/ GM-Tg-rg-IP9473-Ag-2 Rat SIRT6 protein Rat
GM-Tg-mg-IP9473-Ag-1/ GM-Tg-mg-IP9473-Ag-2 Mouse SIRT6 protein Mouse
GM-Tg-cynog-IP9473-Ag-1/ GM-Tg-cynog-IP9473-Ag-2 Cynomolgus/Rhesus macaque SIRT6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9473-Ag-1/ GM-Tg-felg-IP9473-Ag-2 Feline SIRT6 protein Feline
GM-Tg-cang-IP9473-Ag-1/ GM-Tg-cang-IP9473-Ag-2 Canine SIRT6 protein Canine
GM-Tg-bovg-IP9473-Ag-1/ GM-Tg-bovg-IP9473-Ag-2 Bovine SIRT6 protein Bovine
GM-Tg-equg-IP9473-Ag-1/ GM-Tg-equg-IP9473-Ag-2 Equine SIRT6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9473-Ag-1/ GM-Tg-hg-IP9473-Ag-2; GM-Tg-rg-IP9473-Ag-1/ GM-Tg-rg-IP9473-Ag-2;
GM-Tg-mg-IP9473-Ag-1/ GM-Tg-mg-IP9473-Ag-2; GM-Tg-cynog-IP9473-Ag-1/ GM-Tg-cynog-IP9473-Ag-2;
GM-Tg-felg-IP9473-Ag-1/ GM-Tg-felg-IP9473-Ag-2; GM-Tg-cang-IP9473-Ag-1/ GM-Tg-cang-IP9473-Ag-2;
GM-Tg-bovg-IP9473-Ag-1/ GM-Tg-bovg-IP9473-Ag-2; GM-Tg-equg-IP9473-Ag-1/ GM-Tg-equg-IP9473-Ag-2
Products Name SIRT6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SIRT6
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SIRT6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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