SIRT6 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SIRT6 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Target ID GM-IP9473
Target Name SIRT6
Gene Group ldentifer
(Target Gene ID in Homo species)
51548
Gene ID 100063125 (Equus caballus), 101100540 (Felis catus), 299638 (Rattus norvegicus), 485045 (Canis lupus familiaris)
50721 (Mus musculus), 51548 (Homo sapiens), 535416 (Bos taurus), 714545 (Macaca mulatta)
Target Alternative Names 2810449N18Rik,NAD-dependent protein deacetylase sirtuin-6,NAD-dependent protein deacylase sirtuin-6,Protein mono-ADP-ribosyltransferase sirtuin-6,Regulatory protein SIR2 homolog 6 (hSIRT6),SIR2-like protein 6,SIR2L6,SIRT6,Sir2l6,Sirt6,hSIRT6,mSIRT6
Uniprot Accession P59941,Q8N6T7
Protein Sub-location Introcelluar Protein
Category Life Science Target
Gene Ensembl ENSECAG00000015304, ENSCAFG00845006500, ENSMUSG00000034748, ENSG00000077463, ENSBTAG00000019909, ENSMMUG00000019955


Pre-made viral vector of SIRT6 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV000744Human SIRT6/SIR2L6 Lentivirus plasmidNM_001193285.251548HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAD001393Human SIRT6 Adenovirus plasmidNM_001098084.1535416HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC000308Human SIRT6/SIR2L6 Mammalian (Non-Viral Vector) plasmidNM_00119328551548HumanMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001282Human SIRT6/SIR2L6 Lentivirus particleNM_016539.351548HumanLentivirus particleZsGreenNullCMVDetail
vGMLV001431Human SIRT6/SIR2L6 Lentivirus particleNM_016539.451548HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001509Human SIRT6/SIR2L6 Lentivirus particleNM_00119328551548HumanLentivirus particleNull3xflag (C-Terminal)CMVDetail
vGMAD000092Human SIRT6/SIR2L6 Adenovirus particleNM_001193285.251548HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
vGMAD001126Human SIRT6/SIR2L6 Adenovirus particleNM_00119328551548HumanAdenovirus particleNull3xflag (C-Terminal)CMVDetail
pGMAD001159Human SIRT6/hSIRT6/SIR2L6 Adenovirus plasmidNM_016539.451548HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC001299Human SIRT6/hSIRT6/SIR2L6 Mammalian (Non-Viral Vector) plasmidNM_00119328551548HumanMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAD001126Human SIRT6/SIR2L6 Adenovirus plasmidNM_00119328551548HumanAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMAD001159Human SIRT6/hSIRT6/SIR2L6 Adenovirus particleNM_016539.451548HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMAD000092Human SIRT6/SIR2L6 Adenovirus plasmidNM_001193285.251548HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
pGMLV001509Human SIRT6/SIR2L6 Lentivirus plasmidNM_00119328551548HumanLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMLV001431Human SIRT6/SIR2L6 Lentivirus plasmidNM_016539.451548HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001282Human SIRT6/SIR2L6 Lentivirus plasmidNM_016539.351548HumanLentivirus plasmidZsGreenNullCMVDetail
vGMAD001393Human SIRT6 Adenovirus particleNM_001098084.1535416HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
vGMLV000744Human SIRT6/SIR2L6 Lentivirus particleNM_001193285.251548HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001007Rat Sirt6 Lentivirus particleNM_001031649.1299638RatLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001816Rat Sirt6 Adeno-associate virus(AAV) particleNM_001031649.1299638RatAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001007Rat Sirt6 Lentivirus plasmidNM_001031649.1299638RatLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001816Rat Sirt6 Adeno-associate virus(AAV) plasmidNM_001031649.1299638RatAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001600Mouse Sirt6/2810449N18Rik/mSIRT6 Adeno-associate virus(AAV) particleNM_18158650721MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)TIEDetail
vGMAAV001304Mouse Sirt6/2810449N18Rik/AI043036 Adeno-associate virus(AAV) particleNM_181586.450721MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV000943Mouse Sirt6/2810449N18Rik/AI043036 Adeno-associate virus(AAV) particleNM_181586.450721MouseAdeno-associate virus(AAV) particleEGFP3xflag (C-Terminal)CTNTDetail
vGMAAV000513Mouse Sirt6/2810449N18Rik/AI043036 Adeno-associate virus(AAV) particleNM_18158650721MouseAdeno-associate virus(AAV) particleEGFP3xflag (C-Terminal)cTNTDetail
vGMAAV000304Mouse Sirt6/2810449N18Rik/AI043036 Adeno-associate virus(AAV) particleNM_18158650721MouseAdeno-associate virus(AAV) particleGFP3xflag (C-Terminal)CMVDetail
pGMLV001106Mouse sirt6/2810449N18Rik/AI043036 Lentivirus plasmidNM_18158650721MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV000304Mouse Sirt6/2810449N18Rik/AI043036 Adeno-associate virus(AAV) plasmidNM_18158650721MouseAdeno-associate virus(AAV) plasmidGFP3xflag (C-Terminal)CMVDetail
pGMAD000397Mouse Sirt6/2810449N18Rik/AI043036 Adenovirus plasmidNM_18158650721MouseAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAD000397Mouse Sirt6/2810449N18Rik/AI043036 Adenovirus particleNM_18158650721MouseAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
pGMAAV000513Mouse Sirt6/2810449N18Rik/AI043036 Adeno-associate virus(AAV) plasmidNM_18158650721MouseAdeno-associate virus(AAV) plasmidEGFP3xflag (C-Terminal)cTNTDetail
pGMAAV000943Mouse Sirt6/2810449N18Rik/AI043036 Adeno-associate virus(AAV) plasmidNM_181586.450721MouseAdeno-associate virus(AAV) plasmidEGFP3xflag (C-Terminal)CTNTDetail
pGMAAV001304Mouse Sirt6/2810449N18Rik/AI043036 Adeno-associate virus(AAV) plasmidNM_181586.450721MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001600Mouse Sirt6/2810449N18Rik/mSIRT6 Adeno-associate virus(AAV) plasmidNM_18158650721MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)TIEDetail
vGMLV001106Mouse sirt6/2810449N18Rik/AI043036 Lentivirus particleNM_18158650721MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000512Mouse Sirt6/2810449N18Rik/AI043036 Mammalian (Non-Viral Vector) plasmidNM_181586.450721MouseMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail


SIRT6 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo51548Pre-made Human SIRT6/SIR2L6/hSIRT6 siRNA oligo Duplex51548HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo299638Pre-made Rat Sirt6 siRNA oligo Duplex299638RatIn-vitro grade; in-vivo gradeDetail
pGMoligo50721Pre-made Mouse Sirt6/Sir2l6/mSIRT6 siRNA oligo Duplex50721MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo714545Pre-made Cynomolgus/Rhesus macaque SIRT6 siRNA oligo Duplex714545Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101100540Pre-made Cat/Feline SIRT6 siRNA oligo Duplex101100540Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo485045Pre-made Dog/Canine SIRT6 siRNA oligo Duplex485045Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo535416Pre-made Bovines/Cattle SIRT6 siRNA oligo Duplex535416Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100063125Pre-made Equine/Horse SIRT6 siRNA oligo Duplex100063125Equine/HorseIn-vitro grade; in-vivo gradeDetail


SIRT6 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP9473-AbHumanAnti-Human SIRT6 monoclonal antibodymabDetail
GM-Tg-rg-IP9473-AbRatAnti-Rat SIRT6 monoclonal antibodymabDetail
GM-Tg-mg-IP9473-AbMouseAnti-Mouse SIRT6 monoclonal antibodymabDetail
GM-Tg-cynog-IP9473-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque SIRT6 monoclonal antibodymabDetail
GM-Tg-felg-IP9473-AbCat/FelineAnti-Cat/Feline SIRT6 monoclonal antibodymabDetail
GM-Tg-cang-IP9473-AbDog/CanineAnti-Dog/Canine SIRT6 monoclonal antibodymabDetail
GM-Tg-bovg-IP9473-AbBovines/CattleAnti-Bovines/Cattle SIRT6 monoclonal antibodymabDetail
GM-Tg-equg-IP9473-AbEquine/HorseAnti-Equine/Horse SIRT6 monoclonal antibodymabDetail


SIRT6 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP9473-AgHumanHuman SIRT6 recombinant proteinMammalian cellDetail
GM-Tg-rg-IP9473-AgRatRat SIRT6 recombinant proteinMammalian cellDetail
GM-Tg-mg-IP9473-AgMouseMouse SIRT6 recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP9473-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque SIRT6 recombinant proteinMammalian cellDetail
GM-Tg-felg-IP9473-AgCat/FelineCat/Feline SIRT6 recombinant proteinMammalian cellDetail
GM-Tg-cang-IP9473-AgDog/CanineDog/Canine SIRT6 recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP9473-AgBovines/CattleBovines/Cattle SIRT6 recombinant proteinMammalian cellDetail
GM-Tg-equg-IP9473-AgEquine/HorseEquine/Horse SIRT6 recombinant proteinMammalian cellDetail