Recombinant multi-species LEF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LEF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
The Alternative Names of target: 3000002B05,LEF-1,LEF1,Lef-1,Lef1,Lymphoid enhancer-binding factor 1,T cell-specific transcription factor 1-alpha (TCF1-alpha),TCF10,TCF1ALPHA,TCF7L3

Target products collectionGo to LEF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9323-Ag-1/ GM-Tg-hg-IP9323-Ag-2 Human LEF1 protein Human
GM-Tg-rg-IP9323-Ag-1/ GM-Tg-rg-IP9323-Ag-2 Rat LEF1 protein Rat
GM-Tg-mg-IP9323-Ag-1/ GM-Tg-mg-IP9323-Ag-2 Mouse LEF1 protein Mouse
GM-Tg-cynog-IP9323-Ag-1/ GM-Tg-cynog-IP9323-Ag-2 Cynomolgus/Rhesus macaque LEF1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9323-Ag-1/ GM-Tg-felg-IP9323-Ag-2 Feline LEF1 protein Feline
GM-Tg-cang-IP9323-Ag-1/ GM-Tg-cang-IP9323-Ag-2 Canine LEF1 protein Canine
GM-Tg-bovg-IP9323-Ag-1/ GM-Tg-bovg-IP9323-Ag-2 Bovine LEF1 protein Bovine
GM-Tg-equg-IP9323-Ag-1/ GM-Tg-equg-IP9323-Ag-2 Equine LEF1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9323-Ag-1/ GM-Tg-hg-IP9323-Ag-2; GM-Tg-rg-IP9323-Ag-1/ GM-Tg-rg-IP9323-Ag-2;
GM-Tg-mg-IP9323-Ag-1/ GM-Tg-mg-IP9323-Ag-2; GM-Tg-cynog-IP9323-Ag-1/ GM-Tg-cynog-IP9323-Ag-2;
GM-Tg-felg-IP9323-Ag-1/ GM-Tg-felg-IP9323-Ag-2; GM-Tg-cang-IP9323-Ag-1/ GM-Tg-cang-IP9323-Ag-2;
GM-Tg-bovg-IP9323-Ag-1/ GM-Tg-bovg-IP9323-Ag-2; GM-Tg-equg-IP9323-Ag-1/ GM-Tg-equg-IP9323-Ag-2
Products Name LEF1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LEF1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LEF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.