Explore LEF1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
| Target ID |
GM-IP9323
|
| Target Name |
LEF1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
51176
|
| Gene ID |
100072938 (Equus caballus), 101088077 (Felis catus), 161452 (Rattus norvegicus), 16842 (Mus musculus) 478507 (Canis lupus familiaris), 51176 (Homo sapiens), 535399 (Bos taurus), 695776 (Macaca mulatta)
|
| Target Alternative Names |
3000002B05,LEF-1,LEF1,Lef-1,Lef1,Lymphoid enhancer-binding factor 1,T cell-specific transcription factor 1-alpha (TCF1-alpha),TCF10,TCF1ALPHA,TCF7L3
|
| Uniprot Accession |
Q9QXN1,P27782,Q9UJU2
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000019975, ENSMUSG00000027985, ENSCAFG00845029249, ENSG00000138795, ENSBTAG00000006844, ENSMMUG00000023256
|
Pre-made viral vector of LEF1 cDNA Clones/ORF Plasmid
LEF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51176 | Pre-made Human LEF1/LEF-1/TCF10 siRNA oligo Duplex | 51176 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo161452 | Pre-made Rat Lef1 siRNA oligo Duplex | 161452 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16842 | Pre-made Mouse Lef1/Lef-1/3000002B05 siRNA oligo Duplex | 16842 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695776 | Pre-made Cynomolgus/Rhesus macaque LEF1 siRNA oligo Duplex | 695776 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088077 | Pre-made Cat/Feline LEF1 siRNA oligo Duplex | 101088077 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478507 | Pre-made Dog/Canine LEF1 siRNA oligo Duplex | 478507 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535399 | Pre-made Bovines/Cattle LEF1 siRNA oligo Duplex | 535399 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072938 | Pre-made Equine/Horse LEF1 siRNA oligo Duplex | 100072938 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LEF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9323-Ab | Human | Anti-Human LEF1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9323-Ab | Rat | Anti-Rat LEF1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9323-Ab | Mouse | Anti-Mouse LEF1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9323-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LEF1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9323-Ab | Cat/Feline | Anti-Cat/Feline LEF1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9323-Ab | Dog/Canine | Anti-Dog/Canine LEF1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9323-Ab | Bovines/Cattle | Anti-Bovines/Cattle LEF1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9323-Ab | Equine/Horse | Anti-Equine/Horse LEF1 monoclonal antibody | mab | | Detail |
LEF1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9323-Ag | Human | Human LEF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9323-Ag | Rat | Rat LEF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9323-Ag | Mouse | Mouse LEF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9323-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LEF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9323-Ag | Cat/Feline | Cat/Feline LEF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9323-Ag | Dog/Canine | Dog/Canine LEF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9323-Ag | Bovines/Cattle | Bovines/Cattle LEF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9323-Ag | Equine/Horse | Equine/Horse LEF1 recombinant protein | Mammalian cell | Detail |