Recombinant multi-species NFATC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NFATC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]
The Alternative Names of target: 2210017P03Rik,NF-ATC,NF-ATc,NF-ATc1,NF-ATc1.2,NFAT,NFAT transcription complex cytosolic component (NF-ATc,NFAT2,NFATC1,NFATc,NFATc),NFATc1,Nfatc1,Nfatcb,Nuclear factor of activated T-cells,cytoplasmic 1

Target products collectionGo to NFATC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9089-Ag-1/ GM-Tg-hg-IP9089-Ag-2 Human NFATC1 protein Human
GM-Tg-rg-IP9089-Ag-1/ GM-Tg-rg-IP9089-Ag-2 Rat NFATC1 protein Rat
GM-Tg-mg-IP9089-Ag-1/ GM-Tg-mg-IP9089-Ag-2 Mouse NFATC1 protein Mouse
GM-Tg-cynog-IP9089-Ag-1/ GM-Tg-cynog-IP9089-Ag-2 Cynomolgus/Rhesus macaque NFATC1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9089-Ag-1/ GM-Tg-felg-IP9089-Ag-2 Feline NFATC1 protein Feline
GM-Tg-cang-IP9089-Ag-1/ GM-Tg-cang-IP9089-Ag-2 Canine NFATC1 protein Canine
GM-Tg-bovg-IP9089-Ag-1/ GM-Tg-bovg-IP9089-Ag-2 Bovine NFATC1 protein Bovine
GM-Tg-equg-IP9089-Ag-1/ GM-Tg-equg-IP9089-Ag-2 Equine NFATC1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9089-Ag-1/ GM-Tg-hg-IP9089-Ag-2; GM-Tg-rg-IP9089-Ag-1/ GM-Tg-rg-IP9089-Ag-2;
GM-Tg-mg-IP9089-Ag-1/ GM-Tg-mg-IP9089-Ag-2; GM-Tg-cynog-IP9089-Ag-1/ GM-Tg-cynog-IP9089-Ag-2;
GM-Tg-felg-IP9089-Ag-1/ GM-Tg-felg-IP9089-Ag-2; GM-Tg-cang-IP9089-Ag-1/ GM-Tg-cang-IP9089-Ag-2;
GM-Tg-bovg-IP9089-Ag-1/ GM-Tg-bovg-IP9089-Ag-2; GM-Tg-equg-IP9089-Ag-1/ GM-Tg-equg-IP9089-Ag-2
Products Name NFATC1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NFATC1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NFATC1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.