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Target
sublocation: Introcelluar Protein.
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]
| Target ID |
GM-IP9089
|
| Target Name |
NFATC1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4772
|
| Gene ID |
100065378 (Equus caballus), 100361818 (Rattus norvegicus), 101101259 (Felis catus), 18018 (Mus musculus) 4772 (Homo sapiens), 483925 (Canis lupus familiaris), 511224 (Bos taurus), 698089 (Macaca mulatta)
|
| Target Alternative Names |
2210017P03Rik,NF-ATC,NF-ATc,NF-ATc1,NF-ATc1.2,NFAT,NFAT transcription complex cytosolic component (NF-ATc,NFAT2,NFATC1,NFATc,NFATc),NFATc1,Nfatc1,Nfatcb,Nuclear factor of activated T-cells,cytoplasmic 1
|
| Uniprot Accession |
O88942,O95644,P98201
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000019813, ENSMUSG00000033016, ENSG00000131196, ENSCAFG00845000073, ENSBTAG00000000656, ENSMMUG00000022596
|
| Target Classification |
Pathway
|
Pre-made viral vector of NFATC1 cDNA Clones/ORF Plasmid
NFATC1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4772 | Pre-made Human NFATC1/NFAT2/NFATc siRNA oligo Duplex | 4772 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100361818 | Pre-made Rat Nfatc1 siRNA oligo Duplex | 100361818 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18018 | Pre-made Mouse Nfatc1/NFAT2/NFATc siRNA oligo Duplex | 18018 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698089 | Pre-made Cynomolgus/Rhesus macaque NFATC1 siRNA oligo Duplex | 698089 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101259 | Pre-made Cat/Feline NFATC1 siRNA oligo Duplex | 101101259 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483925 | Pre-made Dog/Canine NFATC1 siRNA oligo Duplex | 483925 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511224 | Pre-made Bovines/Cattle NFATC1/NFAT/NF-ATc siRNA oligo Duplex | 511224 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065378 | Pre-made Equine/Horse NFATC1 siRNA oligo Duplex | 100065378 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NFATC1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9089-Ab | Human | Anti-Human NFATC1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9089-Ab | Rat | Anti-Rat NFATC1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9089-Ab | Mouse | Anti-Mouse NFATC1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9089-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NFATC1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9089-Ab | Cat/Feline | Anti-Cat/Feline NFATC1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9089-Ab | Dog/Canine | Anti-Dog/Canine NFATC1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9089-Ab | Bovines/Cattle | Anti-Bovines/Cattle NFATC1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9089-Ab | Equine/Horse | Anti-Equine/Horse NFATC1 monoclonal antibody | mab | | Detail |
NFATC1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9089-Ag | Human | Human NFATC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9089-Ag | Rat | Rat NFATC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9089-Ag | Mouse | Mouse NFATC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9089-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NFATC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9089-Ag | Cat/Feline | Cat/Feline NFATC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9089-Ag | Dog/Canine | Dog/Canine NFATC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9089-Ag | Bovines/Cattle | Bovines/Cattle NFATC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9089-Ag | Equine/Horse | Equine/Horse NFATC1 recombinant protein | Mammalian cell | Detail |