Recombinant multi-species ASL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2510006M18Rik,ASAL,ASL,Argininosuccinate lyase,Arginosuccinase,Asl

Target products collectionGo to ASL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8854-Ag-1/ GM-Tg-hg-IP8854-Ag-2 Human ASL protein Human
GM-Tg-rg-IP8854-Ag-1/ GM-Tg-rg-IP8854-Ag-2 Rat ASL protein Rat
GM-Tg-mg-IP8854-Ag-1/ GM-Tg-mg-IP8854-Ag-2 Mouse ASL protein Mouse
GM-Tg-cynog-IP8854-Ag-1/ GM-Tg-cynog-IP8854-Ag-2 Cynomolgus/Rhesus macaque ASL protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8854-Ag-1/ GM-Tg-felg-IP8854-Ag-2 Feline ASL protein Feline
GM-Tg-cang-IP8854-Ag-1/ GM-Tg-cang-IP8854-Ag-2 Canine ASL protein Canine
GM-Tg-bovg-IP8854-Ag-1/ GM-Tg-bovg-IP8854-Ag-2 Bovine ASL protein Bovine
GM-Tg-equg-IP8854-Ag-1/ GM-Tg-equg-IP8854-Ag-2 Equine ASL protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8854-Ag-1/ GM-Tg-hg-IP8854-Ag-2; GM-Tg-rg-IP8854-Ag-1/ GM-Tg-rg-IP8854-Ag-2;
GM-Tg-mg-IP8854-Ag-1/ GM-Tg-mg-IP8854-Ag-2; GM-Tg-cynog-IP8854-Ag-1/ GM-Tg-cynog-IP8854-Ag-2;
GM-Tg-felg-IP8854-Ag-1/ GM-Tg-felg-IP8854-Ag-2; GM-Tg-cang-IP8854-Ag-1/ GM-Tg-cang-IP8854-Ag-2;
GM-Tg-bovg-IP8854-Ag-1/ GM-Tg-bovg-IP8854-Ag-2; GM-Tg-equg-IP8854-Ag-1/ GM-Tg-equg-IP8854-Ag-2
Products Name ASL protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ASL
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.