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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP8854
|
| Target Name |
ASL
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
435
|
| Gene ID |
100060801 (Equus caballus), 101101529 (Felis catus), 109900 (Mus musculus), 435 (Homo sapiens) 479704 (Canis lupus familiaris), 512771 (Bos taurus), 59085 (Rattus norvegicus), 697109 (Macaca mulatta)
|
| Target Alternative Names |
2510006M18Rik,ASAL,ASL,Argininosuccinate lyase,Arginosuccinase,Asl
|
| Uniprot Accession |
Q91YI0,P04424,Q3SZJ0,P20673
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000012730, ENSMUSG00000025533, ENSG00000126522, ENSCAFG00845013432, ENSBTAG00000015314, ENSMMUG00000011871
|
Pre-made viral vector of ASL cDNA Clones/ORF Plasmid
ASL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo435 | Pre-made Human ASL/ASAL siRNA oligo Duplex | 435 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo59085 | Pre-made Rat Asl siRNA oligo Duplex | 59085 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109900 | Pre-made Mouse Asl/ASAL/2510006M18Rik siRNA oligo Duplex | 109900 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697109 | Pre-made Cynomolgus/Rhesus macaque ASL siRNA oligo Duplex | 697109 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101529 | Pre-made Cat/Feline ASL siRNA oligo Duplex | 101101529 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479704 | Pre-made Dog/Canine ASL siRNA oligo Duplex | 479704 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512771 | Pre-made Bovines/Cattle ASL/ASAL siRNA oligo Duplex | 512771 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060801 | Pre-made Equine/Horse ASL siRNA oligo Duplex | 100060801 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ASL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8854-Ab | Human | Anti-Human ASL monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8854-Ab | Rat | Anti-Rat ASL monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8854-Ab | Mouse | Anti-Mouse ASL monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8854-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ASL monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8854-Ab | Cat/Feline | Anti-Cat/Feline ASL monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8854-Ab | Dog/Canine | Anti-Dog/Canine ASL monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8854-Ab | Bovines/Cattle | Anti-Bovines/Cattle ASL monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8854-Ab | Equine/Horse | Anti-Equine/Horse ASL monoclonal antibody | mab | | Detail |
ASL recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8854-Ag | Human | Human ASL recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8854-Ag | Rat | Rat ASL recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8854-Ag | Mouse | Mouse ASL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8854-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ASL recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8854-Ag | Cat/Feline | Cat/Feline ASL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8854-Ag | Dog/Canine | Dog/Canine ASL recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8854-Ag | Bovines/Cattle | Bovines/Cattle ASL recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8854-Ag | Equine/Horse | Equine/Horse ASL recombinant protein | Mammalian cell | Detail |