Recombinant multi-species MCM2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MCM2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
The Alternative Names of target: BM28,CCNL1,CDCL1,D3S3194,DFNA70,DNA replication licensing factor MCM2,MCM2,MITOTIN,Mcm2,Mcmd2,Minichromosome maintenance protein 2 homolog,Nuclear protein BM28,cdc19,mKIAA0030

Target products collectionGo to MCM2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8812-Ag-1/ GM-Tg-hg-IP8812-Ag-2 Human MCM2 protein Human
GM-Tg-rg-IP8812-Ag-1/ GM-Tg-rg-IP8812-Ag-2 Rat MCM2 protein Rat
GM-Tg-mg-IP8812-Ag-1/ GM-Tg-mg-IP8812-Ag-2 Mouse MCM2 protein Mouse
GM-Tg-cynog-IP8812-Ag-1/ GM-Tg-cynog-IP8812-Ag-2 Cynomolgus/Rhesus macaque MCM2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8812-Ag-1/ GM-Tg-felg-IP8812-Ag-2 Feline MCM2 protein Feline
GM-Tg-cang-IP8812-Ag-1/ GM-Tg-cang-IP8812-Ag-2 Canine MCM2 protein Canine
GM-Tg-bovg-IP8812-Ag-1/ GM-Tg-bovg-IP8812-Ag-2 Bovine MCM2 protein Bovine
GM-Tg-equg-IP8812-Ag-1/ GM-Tg-equg-IP8812-Ag-2 Equine MCM2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8812-Ag-1/ GM-Tg-hg-IP8812-Ag-2; GM-Tg-rg-IP8812-Ag-1/ GM-Tg-rg-IP8812-Ag-2;
GM-Tg-mg-IP8812-Ag-1/ GM-Tg-mg-IP8812-Ag-2; GM-Tg-cynog-IP8812-Ag-1/ GM-Tg-cynog-IP8812-Ag-2;
GM-Tg-felg-IP8812-Ag-1/ GM-Tg-felg-IP8812-Ag-2; GM-Tg-cang-IP8812-Ag-1/ GM-Tg-cang-IP8812-Ag-2;
GM-Tg-bovg-IP8812-Ag-1/ GM-Tg-bovg-IP8812-Ag-2; GM-Tg-equg-IP8812-Ag-1/ GM-Tg-equg-IP8812-Ag-2
Products Name MCM2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MCM2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MCM2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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