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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
| Target ID |
GM-IP8812
|
| Target Name |
MCM2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4171
|
| Gene ID |
100053690 (Equus caballus), 101090176 (Felis catus), 17216 (Mus musculus), 312538 (Rattus norvegicus) 4171 (Homo sapiens), 484622 (Canis lupus familiaris), 510120 (Bos taurus), 710888 (Macaca mulatta)
|
| Target Alternative Names |
BM28,CCNL1,CDCL1,D3S3194,DFNA70,DNA replication licensing factor MCM2,MCM2,MITOTIN,Mcm2,Mcmd2,Minichromosome maintenance protein 2 homolog,Nuclear protein BM28,cdc19,mKIAA0030
|
| Uniprot Accession |
P97310,P49736
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer, Malignant neoplasm of bladder, Malignant neoplasm of prostate
|
| Gene Ensembl |
ENSECAG00000019631, ENSMUSG00000002870, ENSG00000073111, ENSCAFG00845013762, ENSBTAG00000014380, ENSMMUG00000000158
|
Pre-made viral vector of MCM2 cDNA Clones/ORF Plasmid
MCM2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4171 | Pre-made Human MCM2/BM28/CCNL1 siRNA oligo Duplex | 4171 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo312538 | Pre-made Rat Mcm2 siRNA oligo Duplex | 312538 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17216 | Pre-made Mouse Mcm2/BM28/CDCL1 siRNA oligo Duplex | 17216 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710888 | Pre-made Cynomolgus/Rhesus macaque MCM2 siRNA oligo Duplex | 710888 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090176 | Pre-made Cat/Feline MCM2 siRNA oligo Duplex | 101090176 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484622 | Pre-made Dog/Canine MCM2 siRNA oligo Duplex | 484622 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510120 | Pre-made Bovines/Cattle MCM2 siRNA oligo Duplex | 510120 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053690 | Pre-made Equine/Horse MCM2 siRNA oligo Duplex | 100053690 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MCM2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8812-Ab | Human | Anti-Human MCM2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8812-Ab | Rat | Anti-Rat MCM2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8812-Ab | Mouse | Anti-Mouse MCM2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8812-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MCM2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8812-Ab | Cat/Feline | Anti-Cat/Feline MCM2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8812-Ab | Dog/Canine | Anti-Dog/Canine MCM2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8812-Ab | Bovines/Cattle | Anti-Bovines/Cattle MCM2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8812-Ab | Equine/Horse | Anti-Equine/Horse MCM2 monoclonal antibody | mab | | Detail |
MCM2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8812-Ag | Human | Human MCM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8812-Ag | Rat | Rat MCM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8812-Ag | Mouse | Mouse MCM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8812-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MCM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8812-Ag | Cat/Feline | Cat/Feline MCM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8812-Ag | Dog/Canine | Dog/Canine MCM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8812-Ag | Bovines/Cattle | Bovines/Cattle MCM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8812-Ag | Equine/Horse | Equine/Horse MCM2 recombinant protein | Mammalian cell | Detail |