Recombinant multi-species MAGEB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAGEB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CT3.2,Cancer/testis antigen 3.2 (CT3.2),DAM6,DSS-AHC critical interval MAGE superfamily 6 (DAM6),MAGE XP-2 antigen,MAGE-B2 antigen,MAGE-XP-2,MAGEB2,Melanoma-associated antigen B2

Target products collectionGo to MAGEB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8786-Ag-1/ GM-Tg-hg-IP8786-Ag-2 Human MAGEB2 protein Human
GM-Tg-rg-IP8786-Ag-1/ GM-Tg-rg-IP8786-Ag-2 Rat MAGEB2 protein Rat
GM-Tg-mg-IP8786-Ag-1/ GM-Tg-mg-IP8786-Ag-2 Mouse MAGEB2 protein Mouse
GM-Tg-cynog-IP8786-Ag-1/ GM-Tg-cynog-IP8786-Ag-2 Cynomolgus/Rhesus macaque MAGEB2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8786-Ag-1/ GM-Tg-felg-IP8786-Ag-2 Feline MAGEB2 protein Feline
GM-Tg-cang-IP8786-Ag-1/ GM-Tg-cang-IP8786-Ag-2 Canine MAGEB2 protein Canine
GM-Tg-bovg-IP8786-Ag-1/ GM-Tg-bovg-IP8786-Ag-2 Bovine MAGEB2 protein Bovine
GM-Tg-equg-IP8786-Ag-1/ GM-Tg-equg-IP8786-Ag-2 Equine MAGEB2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8786-Ag-1/ GM-Tg-hg-IP8786-Ag-2; GM-Tg-rg-IP8786-Ag-1/ GM-Tg-rg-IP8786-Ag-2;
GM-Tg-mg-IP8786-Ag-1/ GM-Tg-mg-IP8786-Ag-2; GM-Tg-cynog-IP8786-Ag-1/ GM-Tg-cynog-IP8786-Ag-2;
GM-Tg-felg-IP8786-Ag-1/ GM-Tg-felg-IP8786-Ag-2; GM-Tg-cang-IP8786-Ag-1/ GM-Tg-cang-IP8786-Ag-2;
GM-Tg-bovg-IP8786-Ag-1/ GM-Tg-bovg-IP8786-Ag-2; GM-Tg-equg-IP8786-Ag-1/ GM-Tg-equg-IP8786-Ag-2
Products Name MAGEB2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MAGEB2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAGEB2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.