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Target
sublocation: Introcelluar Protein.
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP8786
|
| Target Name |
MAGEB2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4113
|
| Gene ID |
4113 (Homo sapiens), 703594 (Macaca mulatta)
|
| Target Alternative Names |
CT3.2,Cancer/testis antigen 3.2 (CT3.2),DAM6,DSS-AHC critical interval MAGE superfamily 6 (DAM6),MAGE XP-2 antigen,MAGE-B2 antigen,MAGE-XP-2,MAGEB2,Melanoma-associated antigen B2
|
| Uniprot Accession |
O15479
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSG00000099399
|
MAGEB2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4113 | Pre-made Human MAGEB2/DAM6/CT3.2 siRNA oligo Duplex | 4113 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703594 | Pre-made Cynomolgus/Rhesus macaque MAGEB2 siRNA oligo Duplex | 703594 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
MAGEB2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8786-Ab | Human | Anti-Human MAGEB2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8786-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAGEB2 monoclonal antibody | mab | | Detail |
MAGEB2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8786-Ag | Human | Human MAGEB2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8786-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAGEB2 recombinant protein | Mammalian cell | Detail |
