Recombinant multi-species NBR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NBR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
The Alternative Names of target: 1A1-3B,Ca125,Cell migration-inducing gene 19 protein,IAI3B,M17S2,MIG19,Membrane component chromosome 17 surface marker 2,NBR1,Nbr1,Neighbor of BRCA1 gene 1 protein,Next to BRCA1 gene 1 protein,Protein 1A1-3B,RGD1311421,mKIAA0049

Target products collectionGo to NBR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8771-Ag-1/ GM-Tg-hg-IP8771-Ag-2 Human NBR1 protein Human
GM-Tg-rg-IP8771-Ag-1/ GM-Tg-rg-IP8771-Ag-2 Rat NBR1 protein Rat
GM-Tg-mg-IP8771-Ag-1/ GM-Tg-mg-IP8771-Ag-2 Mouse NBR1 protein Mouse
GM-Tg-cynog-IP8771-Ag-1/ GM-Tg-cynog-IP8771-Ag-2 Cynomolgus/Rhesus macaque NBR1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8771-Ag-1/ GM-Tg-felg-IP8771-Ag-2 Feline NBR1 protein Feline
GM-Tg-cang-IP8771-Ag-1/ GM-Tg-cang-IP8771-Ag-2 Canine NBR1 protein Canine
GM-Tg-bovg-IP8771-Ag-1/ GM-Tg-bovg-IP8771-Ag-2 Bovine NBR1 protein Bovine
GM-Tg-equg-IP8771-Ag-1/ GM-Tg-equg-IP8771-Ag-2 Equine NBR1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8771-Ag-1/ GM-Tg-hg-IP8771-Ag-2; GM-Tg-rg-IP8771-Ag-1/ GM-Tg-rg-IP8771-Ag-2;
GM-Tg-mg-IP8771-Ag-1/ GM-Tg-mg-IP8771-Ag-2; GM-Tg-cynog-IP8771-Ag-1/ GM-Tg-cynog-IP8771-Ag-2;
GM-Tg-felg-IP8771-Ag-1/ GM-Tg-felg-IP8771-Ag-2; GM-Tg-cang-IP8771-Ag-1/ GM-Tg-cang-IP8771-Ag-2;
GM-Tg-bovg-IP8771-Ag-1/ GM-Tg-bovg-IP8771-Ag-2; GM-Tg-equg-IP8771-Ag-1/ GM-Tg-equg-IP8771-Ag-2
Products Name NBR1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NBR1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NBR1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.