Explore NBR1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
| Target ID |
GM-IP8771
|
| Target Name |
NBR1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4077
|
| Gene ID |
100051928 (Equus caballus), 101082535 (Felis catus), 17966 (Mus musculus), 303554 (Rattus norvegicus) 4077 (Homo sapiens), 480509 (Canis lupus familiaris), 515032 (Bos taurus), 708558 (Macaca mulatta)
|
| Target Alternative Names |
1A1-3B,Ca125,Cell migration-inducing gene 19 protein,IAI3B,M17S2,MIG19,Membrane component chromosome 17 surface marker 2,NBR1,Nbr1,Neighbor of BRCA1 gene 1 protein,Next to BRCA1 gene 1 protein,Protein 1A1-3B,RGD1311421,mKIAA0049
|
| Uniprot Accession |
P97432,Q501R9,Q14596
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000006950, ENSMUSG00000017119, ENSG00000188554, ENSCAFG00845005914, ENSBTAG00000001632, ENSMMUG00000010433
|
Pre-made viral vector of NBR1 cDNA Clones/ORF Plasmid
NBR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4077 | Pre-made Human NBR1/IAI3B/M17S2 siRNA oligo Duplex | 4077 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo303554 | Pre-made Rat Nbr1/Ca125/RGD1311421 siRNA oligo Duplex | 303554 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17966 | Pre-made Mouse Nbr1/mKIAA0049 siRNA oligo Duplex | 17966 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708558 | Pre-made Cynomolgus/Rhesus macaque NBR1 siRNA oligo Duplex | 708558 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082535 | Pre-made Cat/Feline NBR1 siRNA oligo Duplex | 101082535 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480509 | Pre-made Dog/Canine NBR1 siRNA oligo Duplex | 480509 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515032 | Pre-made Bovines/Cattle NBR1 siRNA oligo Duplex | 515032 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051928 | Pre-made Equine/Horse NBR1 siRNA oligo Duplex | 100051928 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NBR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8771-Ab | Human | Anti-Human NBR1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8771-Ab | Rat | Anti-Rat NBR1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8771-Ab | Mouse | Anti-Mouse NBR1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8771-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NBR1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8771-Ab | Cat/Feline | Anti-Cat/Feline NBR1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8771-Ab | Dog/Canine | Anti-Dog/Canine NBR1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8771-Ab | Bovines/Cattle | Anti-Bovines/Cattle NBR1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8771-Ab | Equine/Horse | Anti-Equine/Horse NBR1 monoclonal antibody | mab | | Detail |
NBR1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8771-Ag | Human | Human NBR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8771-Ag | Rat | Rat NBR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8771-Ag | Mouse | Mouse NBR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8771-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NBR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8771-Ag | Cat/Feline | Cat/Feline NBR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8771-Ag | Dog/Canine | Dog/Canine NBR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8771-Ag | Bovines/Cattle | Bovines/Cattle NBR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8771-Ag | Equine/Horse | Equine/Horse NBR1 recombinant protein | Mammalian cell | Detail |