Recombinant multi-species Cytokeratin 8/KRT8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cytokeratin 8/KRT8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
The Alternative Names of target: CARD2,CK-8,CK8,CYK8,CYKER,Card2,Cytokeratin 8,Cytokeratin-8 (CK-8),EndoA,K2C8,K8,KO,KRT2-8,KRT8,Keratin,Keratin-8 (K8),Krt-2.8,Krt2-8,Krt8,TROMA-1,Type-II keratin Kb8,type II cytoskeletal 8

Target products collectionGo to Cytokeratin 8/KRT8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8430-Ag-1/ GM-Tg-hg-IP8430-Ag-2 Human Cytokeratin 8/KRT8 protein Human
GM-Tg-rg-IP8430-Ag-1/ GM-Tg-rg-IP8430-Ag-2 Rat Cytokeratin 8/KRT8 protein Rat
GM-Tg-mg-IP8430-Ag-1/ GM-Tg-mg-IP8430-Ag-2 Mouse Cytokeratin 8/KRT8 protein Mouse
GM-Tg-cynog-IP8430-Ag-1/ GM-Tg-cynog-IP8430-Ag-2 Cynomolgus/Rhesus macaque Cytokeratin 8/KRT8 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8430-Ag-1/ GM-Tg-felg-IP8430-Ag-2 Feline Cytokeratin 8/KRT8 protein Feline
GM-Tg-cang-IP8430-Ag-1/ GM-Tg-cang-IP8430-Ag-2 Canine Cytokeratin 8/KRT8 protein Canine
GM-Tg-bovg-IP8430-Ag-1/ GM-Tg-bovg-IP8430-Ag-2 Bovine Cytokeratin 8/KRT8 protein Bovine
GM-Tg-equg-IP8430-Ag-1/ GM-Tg-equg-IP8430-Ag-2 Equine Cytokeratin 8/KRT8 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8430-Ag-1/ GM-Tg-hg-IP8430-Ag-2; GM-Tg-rg-IP8430-Ag-1/ GM-Tg-rg-IP8430-Ag-2;
GM-Tg-mg-IP8430-Ag-1/ GM-Tg-mg-IP8430-Ag-2; GM-Tg-cynog-IP8430-Ag-1/ GM-Tg-cynog-IP8430-Ag-2;
GM-Tg-felg-IP8430-Ag-1/ GM-Tg-felg-IP8430-Ag-2; GM-Tg-cang-IP8430-Ag-1/ GM-Tg-cang-IP8430-Ag-2;
GM-Tg-bovg-IP8430-Ag-1/ GM-Tg-bovg-IP8430-Ag-2; GM-Tg-equg-IP8430-Ag-1/ GM-Tg-equg-IP8430-Ag-2
Products Name Cytokeratin 8/KRT8 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Cytokeratin 8/KRT8
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cytokeratin 8/KRT8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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