Cytokeratin 8/KRT8 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Cytokeratin 8/KRT8 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Target ID GM-IP8430
Target Name Cytokeratin 8/KRT8
Gene Group ldentifer
（Target Gene ID in Homo species) 		3856
Gene ID 101081312 (Felis catus), 16691 (Mus musculus), 25626 (Rattus norvegicus), 281269 (Bos taurus)
3856 (Homo sapiens), 486513 (Canis lupus familiaris), 700449 (Macaca mulatta)
Target Alternative Names CARD2,CK-8,CK8,CYK8,CYKER,Card2,Cytokeratin 8,Cytokeratin-8 (CK-8),EndoA,K2C8,K8,KO,KRT2-8,KRT8,Keratin,Keratin-8 (K8),Krt-2.8,Krt2-8,Krt8,TROMA-1,Type-II keratin Kb8,type II cytoskeletal 8
Uniprot Accession P11679,Q10758,P05786,P05787
Protein Sub-location Introcelluar Protein
Category Life Science Target
Disease cancer, Ovary Cancer, Congenital occlusion of ureteropelvic junction
Gene Ensembl ENSMUSG00000049382, ENSBTAG00000000836, ENSG00000170421


Pre-made viral vector of Cytokeratin 8/KRT8 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001399Human KRT8/CARD2/CK-8 Lentivirus plasmidNM_0022733856HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAD000826Human KRT8/CARD2/CK-8 Adenovirus plasmidNM_0022733856HumanAdenovirus plasmidmCherry3xflag (C-Terminal)EF1Detail
pGMAP000299Human KRT8/CARD2/CK8 Adenovirus plasmidBC0758393856HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
pGMPC001417Human KRT8/CARD2/CK-8 Mammalian (Non-Viral Vector) plasmidNM_002273.43856HumanMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLP001399Human KRT8/CARD2/CK-8 Lentivirus particleNM_0022733856HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000826Human KRT8/CARD2/CK-8 Adenovirus particleNM_0022733856HumanAdenovirus particlemCherry3xflag (C-Terminal)EF1Detail
vGMAP000299Human KRT8/CARD2/CK8 Adenovirus particleBC0758393856HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
pGMLV001342Rat KRT8/CYKER/Krt2-8 Lentivirus plasmidNM_199370.125626RatLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMAD000814Rat Krt8/CYKER/Krt2-8 Adenovirus plasmidNM_199370.125626RatAdenovirus plasmidmCherry3xflag (C-Terminal)CMVDetail
vGMLV001342Rat KRT8/CYKER/Krt2-8 Lentivirus particleNM_199370.125626RatLentivirus particleNull3xflag (C-Terminal)CMVDetail
vGMAD000814Rat Krt8/CYKER/Krt2-8 Adenovirus particleNM_199370.125626RatAdenovirus particlemCherry3xflag (C-Terminal)CMVDetail
pGMLPm002349Mouse Krt8/AA960620/AL022697 Lentivirus plasmidNM_03117016691MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm002349Mouse Krt8/AA960620/AL022697 Lentivirus particleNM_03117016691MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


Cytokeratin 8/KRT8 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3856Pre-made Human KRT8/K8/KO siRNA oligo Duplex3856HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo25626Pre-made Rat Krt8/CYKER/Krt2-8 siRNA oligo Duplex25626RatIn-vitro grade; in-vivo gradeDetail
pGMoligo16691Pre-made Mouse Krt8/K8/Card2 siRNA oligo Duplex16691MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo700449Pre-made Cynomolgus/Rhesus macaque KRT8 siRNA oligo Duplex700449Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101081312Pre-made Cat/Feline KRT8 siRNA oligo Duplex101081312Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo486513Pre-made Dog/Canine KRT8 siRNA oligo Duplex486513Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo281269Pre-made Bovines/Cattle KRT8/KRT2-8 siRNA oligo Duplex281269Bovines/CattleIn-vitro grade; in-vivo gradeDetail


Cytokeratin 8/KRT8 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP8430-AbHumanAnti-Human Cytokeratin 8/KRT8 monoclonal antibodymabDetail
GM-Tg-rg-IP8430-AbRatAnti-Rat Cytokeratin 8/KRT8 monoclonal antibodymabDetail
GM-Tg-mg-IP8430-AbMouseAnti-Mouse Cytokeratin 8/KRT8 monoclonal antibodymabDetail
GM-Tg-cynog-IP8430-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Cytokeratin 8/KRT8 monoclonal antibodymabDetail
GM-Tg-felg-IP8430-AbCat/FelineAnti-Cat/Feline Cytokeratin 8/KRT8 monoclonal antibodymabDetail
GM-Tg-cang-IP8430-AbDog/CanineAnti-Dog/Canine Cytokeratin 8/KRT8 monoclonal antibodymabDetail
GM-Tg-bovg-IP8430-AbBovines/CattleAnti-Bovines/Cattle Cytokeratin 8/KRT8 monoclonal antibodymabDetail


Cytokeratin 8/KRT8 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP8430-AgHumanHuman Cytokeratin 8/KRT8 recombinant proteinMammalian cellDetail
GM-Tg-rg-IP8430-AgRatRat Cytokeratin 8/KRT8 recombinant proteinMammalian cellDetail
GM-Tg-mg-IP8430-AgMouseMouse Cytokeratin 8/KRT8 recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP8430-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Cytokeratin 8/KRT8 recombinant proteinMammalian cellDetail
GM-Tg-felg-IP8430-AgCat/FelineCat/Feline Cytokeratin 8/KRT8 recombinant proteinMammalian cellDetail
GM-Tg-cang-IP8430-AgDog/CanineDog/Canine Cytokeratin 8/KRT8 recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP8430-AgBovines/CattleBovines/Cattle Cytokeratin 8/KRT8 recombinant proteinMammalian cellDetail