Recombinant multi-species EIF6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
The Alternative Names of target: 1110004P11,B(2)GCN homolog,B4 integrin interactor,CAB,EIF3A,EIF6,Eif6,Eukaryotic translation initiation factor 6,ITGB4BP,Itgb4bp,b(2)gcn,eIF-6,imc-415,p27(BBP),p27BBP

Target products collectionGo to EIF6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8320-Ag-1/ GM-Tg-hg-IP8320-Ag-2 Human EIF6 protein Human
GM-Tg-rg-IP8320-Ag-1/ GM-Tg-rg-IP8320-Ag-2 Rat EIF6 protein Rat
GM-Tg-mg-IP8320-Ag-1/ GM-Tg-mg-IP8320-Ag-2 Mouse EIF6 protein Mouse
GM-Tg-cynog-IP8320-Ag-1/ GM-Tg-cynog-IP8320-Ag-2 Cynomolgus/Rhesus macaque EIF6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8320-Ag-1/ GM-Tg-felg-IP8320-Ag-2 Feline EIF6 protein Feline
GM-Tg-cang-IP8320-Ag-1/ GM-Tg-cang-IP8320-Ag-2 Canine EIF6 protein Canine
GM-Tg-bovg-IP8320-Ag-1/ GM-Tg-bovg-IP8320-Ag-2 Bovine EIF6 protein Bovine
GM-Tg-equg-IP8320-Ag-1/ GM-Tg-equg-IP8320-Ag-2 Equine EIF6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8320-Ag-1/ GM-Tg-hg-IP8320-Ag-2; GM-Tg-rg-IP8320-Ag-1/ GM-Tg-rg-IP8320-Ag-2;
GM-Tg-mg-IP8320-Ag-1/ GM-Tg-mg-IP8320-Ag-2; GM-Tg-cynog-IP8320-Ag-1/ GM-Tg-cynog-IP8320-Ag-2;
GM-Tg-felg-IP8320-Ag-1/ GM-Tg-felg-IP8320-Ag-2; GM-Tg-cang-IP8320-Ag-1/ GM-Tg-cang-IP8320-Ag-2;
GM-Tg-bovg-IP8320-Ag-1/ GM-Tg-bovg-IP8320-Ag-2; GM-Tg-equg-IP8320-Ag-1/ GM-Tg-equg-IP8320-Ag-2
Products Name EIF6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EIF6
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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