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Target
sublocation: Introcelluar Protein.
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
| Target ID |
GM-IP8320
|
| Target Name |
EIF6
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3692
|
| Gene ID |
100054650 (Equus caballus), 101082644 (Felis catus), 16418 (Mus musculus), 286811 (Bos taurus) 305506 (Rattus norvegicus), 3692 (Homo sapiens), 477210 (Canis lupus familiaris), 709602 (Macaca mulatta)
|
| Target Alternative Names |
1110004P11,B(2)GCN homolog,B4 integrin interactor,CAB,EIF3A,EIF6,Eif6,Eukaryotic translation initiation factor 6,ITGB4BP,Itgb4bp,b(2)gcn,eIF-6,imc-415,p27(BBP),p27BBP
|
| Uniprot Accession |
O55135,Q9TU47,Q3KRD8,P56537
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000010701, ENSMUSG00000027613, ENSBTAG00000011263, ENSG00000242372, ENSCAFG00845018936, ENSMMUG00000018208
|
Pre-made viral vector of EIF6 cDNA Clones/ORF Plasmid
EIF6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3692 | Pre-made Human EIF6/CAB/EIF3A siRNA oligo Duplex | 3692 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo305506 | Pre-made Rat Eif6/eIF-6/Itgb4bp siRNA oligo Duplex | 305506 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16418 | Pre-made Mouse Eif6/CAB/eIF-6 siRNA oligo Duplex | 16418 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709602 | Pre-made Cynomolgus/Rhesus macaque EIF6/ITGB4BP siRNA oligo Duplex | 709602 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082644 | Pre-made Cat/Feline EIF6 siRNA oligo Duplex | 101082644 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477210 | Pre-made Dog/Canine EIF6/ITGB4BP siRNA oligo Duplex | 477210 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286811 | Pre-made Bovines/Cattle EIF6/ITGB4BP siRNA oligo Duplex | 286811 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054650 | Pre-made Equine/Horse EIF6 siRNA oligo Duplex | 100054650 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EIF6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8320-Ab | Human | Anti-Human EIF6 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8320-Ab | Rat | Anti-Rat EIF6 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8320-Ab | Mouse | Anti-Mouse EIF6 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8320-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EIF6 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8320-Ab | Cat/Feline | Anti-Cat/Feline EIF6 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8320-Ab | Dog/Canine | Anti-Dog/Canine EIF6 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8320-Ab | Bovines/Cattle | Anti-Bovines/Cattle EIF6 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8320-Ab | Equine/Horse | Anti-Equine/Horse EIF6 monoclonal antibody | mab | | Detail |
EIF6 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8320-Ag | Human | Human EIF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8320-Ag | Rat | Rat EIF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8320-Ag | Mouse | Mouse EIF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8320-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EIF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8320-Ag | Cat/Feline | Cat/Feline EIF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8320-Ag | Dog/Canine | Dog/Canine EIF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8320-Ag | Bovines/Cattle | Bovines/Cattle EIF6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8320-Ag | Equine/Horse | Equine/Horse EIF6 recombinant protein | Mammalian cell | Detail |