Recombinant multi-species ACC1/ACACA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ACC1/ACACA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: A530025K05Rik,ACAC,ACACA,ACACAD,ACACalpha,ACC,ACC1,ACCA,ACCalpha,Acac,Acac1,Acaca,Acc1,Acetyl-CoA carboxylase 1,Acetyl-Coenzyme A carboxylase alpha (ACC-alpha),Gm738,hACC1

Target products collectionGo to ACC1/ACACA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7940-Ag-1/ GM-Tg-hg-IP7940-Ag-2 Human ACC1/ACACA protein Human
GM-Tg-rg-IP7940-Ag-1/ GM-Tg-rg-IP7940-Ag-2 Rat ACC1/ACACA protein Rat
GM-Tg-mg-IP7940-Ag-1/ GM-Tg-mg-IP7940-Ag-2 Mouse ACC1/ACACA protein Mouse
GM-Tg-cynog-IP7940-Ag-1/ GM-Tg-cynog-IP7940-Ag-2 Cynomolgus/Rhesus macaque ACC1/ACACA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7940-Ag-1/ GM-Tg-felg-IP7940-Ag-2 Feline ACC1/ACACA protein Feline
GM-Tg-cang-IP7940-Ag-1/ GM-Tg-cang-IP7940-Ag-2 Canine ACC1/ACACA protein Canine
GM-Tg-bovg-IP7940-Ag-1/ GM-Tg-bovg-IP7940-Ag-2 Bovine ACC1/ACACA protein Bovine
GM-Tg-equg-IP7940-Ag-1/ GM-Tg-equg-IP7940-Ag-2 Equine ACC1/ACACA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7940-Ag-1/ GM-Tg-hg-IP7940-Ag-2; GM-Tg-rg-IP7940-Ag-1/ GM-Tg-rg-IP7940-Ag-2;
GM-Tg-mg-IP7940-Ag-1/ GM-Tg-mg-IP7940-Ag-2; GM-Tg-cynog-IP7940-Ag-1/ GM-Tg-cynog-IP7940-Ag-2;
GM-Tg-felg-IP7940-Ag-1/ GM-Tg-felg-IP7940-Ag-2; GM-Tg-cang-IP7940-Ag-1/ GM-Tg-cang-IP7940-Ag-2;
GM-Tg-bovg-IP7940-Ag-1/ GM-Tg-bovg-IP7940-Ag-2; GM-Tg-equg-IP7940-Ag-1/ GM-Tg-equg-IP7940-Ag-2
Products Name ACC1/ACACA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ACC1/ACACA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ACC1/ACACA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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