Explore ACC1/ACACA gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP7940
|
| Target Name |
ACC1/ACACA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
31
|
| Gene ID |
100071472 (Equus caballus), 101083046 (Felis catus), 107476 (Mus musculus), 281590 (Bos taurus) 31 (Homo sapiens), 491130 (Canis lupus familiaris), 60581 (Rattus norvegicus), 714218 (Macaca mulatta)
|
| Target Alternative Names |
A530025K05Rik,ACAC,ACACA,ACACAD,ACACalpha,ACC,ACC1,ACCA,ACCalpha,Acac,Acac1,Acaca,Acc1,Acetyl-CoA carboxylase 1,Acetyl-Coenzyme A carboxylase alpha (ACC-alpha),Gm738,hACC1
|
| Uniprot Accession |
Q5SWU9,Q9TTS3,Q13085,P11497
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000010631, ENSMUSG00000020532, ENSBTAG00000017567, ENSG00000278540, ENSCAFG00845007007, ENSMMUG00000009349
|
ACC1/ACACA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo31 | Pre-made Human ACACA/ACC/ACAC siRNA oligo Duplex | 31 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60581 | Pre-made Rat Acaca/ACC1/Acac siRNA oligo Duplex | 60581 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107476 | Pre-made Mouse Acaca/Acac/Acc1 siRNA oligo Duplex | 107476 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714218 | Pre-made Cynomolgus/Rhesus macaque ACACA siRNA oligo Duplex | 714218 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083046 | Pre-made Cat/Feline ACACA siRNA oligo Duplex | 101083046 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491130 | Pre-made Dog/Canine ACACA siRNA oligo Duplex | 491130 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281590 | Pre-made Bovines/Cattle ACACA/ACC1/ACCA siRNA oligo Duplex | 281590 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071472 | Pre-made Equine/Horse ACACA siRNA oligo Duplex | 100071472 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ACC1/ACACA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP7940-Ab | Human | Anti-Human ACC1/ACACA monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP7940-Ab | Rat | Anti-Rat ACC1/ACACA monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP7940-Ab | Mouse | Anti-Mouse ACC1/ACACA monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP7940-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ACC1/ACACA monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP7940-Ab | Cat/Feline | Anti-Cat/Feline ACC1/ACACA monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP7940-Ab | Dog/Canine | Anti-Dog/Canine ACC1/ACACA monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP7940-Ab | Bovines/Cattle | Anti-Bovines/Cattle ACC1/ACACA monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP7940-Ab | Equine/Horse | Anti-Equine/Horse ACC1/ACACA monoclonal antibody | mab | | Detail |
ACC1/ACACA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP7940-Ag | Human | Human ACC1/ACACA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP7940-Ag | Rat | Rat ACC1/ACACA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP7940-Ag | Mouse | Mouse ACC1/ACACA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP7940-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ACC1/ACACA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP7940-Ag | Cat/Feline | Cat/Feline ACC1/ACACA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP7940-Ag | Dog/Canine | Dog/Canine ACC1/ACACA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP7940-Ag | Bovines/Cattle | Bovines/Cattle ACC1/ACACA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP7940-Ag | Equine/Horse | Equine/Horse ACC1/ACACA recombinant protein | Mammalian cell | Detail |